Polymorphism and Crystallisation: Chemical Development Issues

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The reproducible production of organic crystals in the correct form (habit, solvate, polymorph) and particle size is a source of much heart-ache. Although production of new polymorphs and solvates can be a source of profit for companies through extension of the patent lifetime, the inability to manufacture a consistent crystalline form often leads to costly project delays, particularly in chemical development.

This conference will focus on these issues from the viewpoint of the process chemist and chemical engineer; i.e., on chemical development issues which impact the ability to routinely manufacture the chosen crystalline form, whether this be the most stable or a metastable crystal.

Case studies from different companies will show how different organisations identify and solve these extremely difficult issues in different ways, depending on how far the project is along the development time line.

Experts in the field will also give lectures on problem solving and troubleshooting, as well as giving insight into new techniques, (supercritical fluids, polymorph prediction etc.) which will be of value in the future.

Who Should Attend?

• Process Research & Development Chemists
• Organic Chemists & Chemical Engineers
• Anyone involved in Chemical Development and Manufacturing
• Anyone working with Crystallization and Solid Form Issues

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