Total Synthesis of Nanoparticles

  • Author: David Bradley
  • Published: 17 November 2011
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
  • Source / Publisher: Nature Chemistry/Nature Publishing Group
thumbnail image: Total Synthesis of Nanoparticles

US chemists at Pennsylvania State University have developed a framework for the total synthesis of nanoparticles using processes analogous to the reactions in a synthetic scheme. The system uses solid-state nanoparticle analogs of chemoselective reactions, regiospecificity, coupling reactions, and molecular substituent effects to construct sophisticated hybrid nanoparticle oligomers. These artificial "molecules" are synthesized in a predictable and stepwise manner from organometallic building blocks.


The approach could allow multifunctional lab-on-a-particle systems to be developed for solar energy conversion, fuel-cell catalysis, medical imaging, and electronics.


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