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Advanced Materials

Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy

Published: 23 February 2018

Author(s): Gregor Fuhrmann, Rona Chandrawati, Paresh A. Parmar, Timothy J. Keane, Stephanie A. Maynard, Sergio Bertazzo, Molly M. Stevens

Abstract Extracellular vesicles (EVs) have recently gained significant attention as important mediators of intercellular communication, potential drug carriers, and disease biomarkers. These natural cell‐derived nanoparticles are postulated to be biocompatible, stable under physiological conditions, and to show reduced immunogenicity as compared to other synthetic nanoparticles. Although initial clinical trials are ongoing, the use...

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Advanced Materials

Quantum Emitters in Hexagonal Boron Nitride Have Spectrally Tunable Quantum Efficiency

Published: 23 February 2018

Author(s): Andreas W. Schell, Mikael Svedendahl, Romain Quidant

Abstract Understanding the properties of novel solid‐state quantum emitters is pivotal for a variety of applications in research fields ranging from quantum optics to biology. Recently discovered defects in hexagonal boron nitride are especially interesting, as they offer much desired characteristics such as narrow emission lines and photostability. Here, the dependence of the emission on the excitation wavelength is studied. It is...

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Advanced Materials

Oxide Thin‐Film Electronics using All‐MXene Electrical Contacts

Published: 23 February 2018

Author(s): Zhenwei Wang, Hyunho Kim, Husam N. Alshareef

Abstract 2D MXenes have shown great promise in electrochemical and electromagnetic shielding applications. However, their potential use in electronic devices is significantly less explored. The unique combination of metallic conductivity and hydrophilic surface suggests that MXenes can also be promising in electronics and sensing applications. Here, it is shown that metallic Ti3C2 MXene with work function of 4.60 eV can make good...

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Advanced Materials

Highly Augmented Drug Loading and Stability of Micellar Nanocomplexes Composed of Doxorubicin and Poly(ethylene glycol)–Green Tea Catechin Conjugate for Cancer Therapy

Published: 23 February 2018

Author(s): Kun Liang, Joo Eun Chung, Shu Jun Gao, Nunnarpas Yongvongsoontorn, Motoichi Kurisawa

Abstract Low drug loading and instability in blood circulation are two key challenges that impede the successful clinical translation of nanomedicine, as they result in only marginal therapeutic efficacy and toxic side effects associated with premature drug leakage, respectively. Herein, highly stable and ultrahigh drug loading micellar nanocomplexes (MNCs) based on the self‐assembly of the anticancer drug doxorubicin (DOX) and a...

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Advanced Materials

Direct Growth of Highly Stable Patterned Graphene on Dielectric Insulators using a Surface‐Adhered Solid Carbon Source

Published: 23 February 2018

Author(s): Eunho Lee, Seung Goo Lee, Hyo Chan Lee, Mankyu Jo, Min Seok Yoo, Kilwon Cho

Abstract A novel method is described for the direct growth of patterned graphene on dielectric substrates by chemical vapor deposition (CVD) in the presence of Cu vapor and using a solid aromatic carbon source, 1,2,3,4‐tetraphenylnapthalene (TPN), as the precursor. The UV/O3 treatment of the TPN film both crosslinks TPN and results in a strong interaction between the substrate and the TPN that prevents complete sublimation of the...

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Basic & Clinical Pharmacology & Toxicology

Silica Nanoparticle‐induced Cytokine Responses in BEAS‐2B and HBEC3‐KT Cells: Significance of Particle Size and Signalling Pathways in Different Lung Cell Cultures

Published: 23 February 2018

Author(s): Marit Låg, Tonje Skuland, Anna Godymchuk, Thu H. T. Nguyen, Hang L. T. Pham, Magne Refsnes

Abstract We have previously reported that silica nanoparticles (SiNPs) of nominal size 50 nm (Si50) induce the pro‐inflammatory cytokines CXCL8 and IL‐6 in BEAS‐2B cells, via mechanisms involving MAPK p38, TACE‐mediated TGF‐α release and the NF‐κB pathway. In this study, we examined whether these findings are cell specific or might be extended to another epithelial lung cell model, HBEC3‐KT, and also to SiNPs of a smaller size...

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Journal of the Science of Food and Agriculture

The effect of cooking temperature on the aggregation and digestion rate of myofibrillar proteins in Jinhua ham

Published: 23 February 2018

Author(s): Chang‐Yu Zhou, Dao‐Dong Pan, Yang‐Ying Sun, Chun‐Bao Li, Xing‐Lian Xu, Jin‐Xuan Cao, Guang‐Hong Zhou

Abstract BACKGROUND In order to evaluate the effect of cooking temperature on the nutrition quality of dry‐cured hams, 60 biceps femoris samples from 16 Jinhua hams were divided into four groups (control, 70, 100 and 120 °C) and cooked for 30 min. Carbonyl content, sulfhydryl groups, surface hydrophobicity, microstructure, protein aggregation and digestibility of myofibrillar proteins were investigated. ...

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Pest Management Science

Binding targets of termiticidal lectins from the bark and leaf of Myracrodruon urundeuva in the gut of Nasutitermes corniger workers

Published: 23 February 2018

Author(s): Thâmarah A Lima, Leonardo P Dornelles, Ana Patrícia S Oliveira, Caio CS Guedes, Sueden O Souza, Roberto A Sá, Russolina B Zingali, Thiago H Napoleão, Patrícia MG Paiva

Abstract BACKGROUND Lectins, carbohydrate‐binding proteins, from the bark (MuBL) and leaf (MuLL) of Myracrodruon urundeuva are termiticidal agents against Nasutitermes corniger workers and have been shown to induce oxidative stress and cell death in the midgut of these insects. In this study, we investigated the binding targets of MuBL and MuLL in the gut of N. corniger workers by determining the effects of these lectins on the...

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Pest Management Science

Factors driving public tolerance levels and information‐seeking behaviour concerning insects in the household environment

Published: 23 February 2018

Author(s): Bruce Schoelitsz, P Marijn Poortvliet, Willem Takken

Abstract BACKGROUND The public's negative attitudes towards household insects drive tolerance for these insects and their control. Tolerance levels are important in integrated pest management (IPM), as are pest knowledge and information. The risk information seeking and processing (RISP) model describes the relationships between personal factors and information‐seeking behaviour. We combined IPM and...

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Pest Management Science

Remarkably efficient production of a highly insecticidal Chrysodeixis chalcites nucleopolyhedrovirus (ChchNPV) isolate in its homologous host

Published: 23 February 2018

Author(s): Alexandra Bernal, Oihane Simón, Trevor Williams, Delia Muñoz, Primitivo Caballero

Abstract BACKGROUND A Chrysodeixis chalcites nucleopolyhedrovirus from the Canary Islands (ChchNPV‐TF1) has proved to be effective for control of Chrysodeixis chalcites on banana crops. Commercialization of this virus as a bioinsecticide requires an efficient production system. RESULTS The sixth instar (L6) was the most suitable for virus production, producing 1.80...

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Most-accessed articles from each ChemPubSoc Europe, ACES, and GDCh journal

January 2018


New Academicians and Foreign Members of the Chinese Academy of Sciences [News]
Angew. Chem. Int. Ed. 2018, vol. 57, p. 1445

Michael Dirkmann, Javier Iglesias-Fernández, Victor Muñoz, Pandian Sokkar, Christoph Rumancev, Andreas von Gundlach, Oktavian Krenczyk, Tobias Vöpel, Julia Nowack, Martin A. Schroer, Simon Ebbinghaus, Christian Herrmann, Axel Rosenhahn, Elsa Sanchez-Garcia, Frank Schulz
A Multiperspective Approach to Solvent Regulation of Enzymatic Activity: HMG-CoA Reductase [Communication]
ChemBioChem 2018, vol. 19, p. 153

Isabela C. Man, Hai-Yan Su, Federico Calle-Vallejo, Heine A. Hansen, José I. Martínez, Nilay G. Inoglu, John Kitchin, Thomas F. Jaramillo, Jens K. Nørskov, Jan Rossmeisl
Universality in Oxygen Evolution Electrocatalysis on Oxide Surfaces [Full Paper]
ChemCatChem 2011, vol. 3, p. 1159

Matthias Ducci
Geheimtinten [Artikel]
Chem. Unserer Zeit 2017, vol. 51, p. 228

Balaram Mukhopadhyay, Rituparna Das
Chemical O-Glycosylations: An Overview [Review]
ChemistryOpen 2016, vol. 5, p. 401

Lei Han, Meng-Ke Wu, Fei-Yan Yi, Dongxiao Chen, Hai-Long Jiang
Chemical Sensors Based on Metal-Organic Frameworks [Review]
ChemPlusChem 2016, vol. 81, p. 675

Miaofang Chi, Harry M. Meyer, Zili Wu, Liangbo Liang, Peter V. Bonnesen, Dale K. Hensley, Rui Peng, Yang Song, Cheng Ma, Bobby G. Sumpter, Adam J. Rondinone
High-Selectivity Electrochemical Conversion of CO2 to Ethanol using a Copper Nanoparticle/N-Doped Graphene Electrode [Full Paper]
ChemistrySelect 2016, vol. 1, p. 6055

Ekkehard Schwab, Sebastian Schiebahn, Georg Schaub, Martin Reuter, Konstantin Räuchle, Ludolf Plass, Marcell Peuckert, Anja Metzelthin, Falko Mahlendorf, Wolfram Koch, Renate Hoer, Angelika Heinzel, Sigmar Bräuninger, Martin Bertau, Christian Beilmann, Florian Ausfelder, Ferdi Schüth, Detlef Stolten, Gisa Teßmer, Kurt Wagemann, Karl-Friedrich Ziegahn
Energiespeicherung als Element einer sicheren Energieversorgung [Übersichtsbeitrag]
Chem. Ing. Tech. 2015, vol. 87, p. 17

Abas Mohsenzadeh, Akram Zamani, Mohammad J. Taherzadeh
Bioethylene Production from Ethanol: A Review and Techno-economical Evaluation [Review]
ChemBioEng Rev. 2017, vol. 4, p. 75

Lantao Liu, Yanli Zhou, Shuang Liu, Maotian Xu
The Applications of Metal−Organic Frameworks in Electrochemical Sensors [Review]
ChemElectroChem 2018, vol. 5, p. 6

Yinghui Xue, Qin Zhang, Tao Zhang, Lei Fu
Black Phosphorus: Properties, Synthesis, and Applications in Energy Conversion and Storage [Focus Review]
ChemNanoMat 2017, vol. 3, p. 352

Haymo Ross
We are Family (Chemistry Smash Hits) [Editorial]
Chem. Eur. J. 2018, vol. 24, p. 6

Xinzhe Shi, Arpan Sasmal, Jean-François Soulé, Henri Doucet
Metal-Catalyzed C−H Bond Activation of 5-Membered Carbocyclic Rings: A Powerful Access to Azulene, Acenaphthylene and Fulvene Derivatives [Focus Review]
Chem. Asian J. 2018, vol. 13, p. 143

Andrea Gualandi, Luca Mengozzi, Pier Giorgio Cozzi
Iron-Promoted Radical Reactions: Current Status and Perspectives [Focus Review]
Asian J. Org. Chem. 2017, vol. 6, p. 1160

Truong-Thanh Tung, Trong T. Dao, Marta G. Junyent, Michael Palmgren, Thomas Günther-Pomorski, Anja T. Fuglsang, Søren B. Christensen, John Nielsen
Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+-ATPase Inhibitors (ChemMedChem 1/2018) [Cover Picture]
ChemMedChem 2018, vol. 13, p. 2

Zhoufeng Bian, Sonali Das, Ming Hui Wai, Plaifa Hongmanorom, Sibudjing Kawi
A Review on Bimetallic Nickel-Based Catalysts for CO2 Reforming of Methane [Review]
ChemPhysChem 2017, vol. 18, p. 3117

Dogukan Hazar Apaydin, Dong Ryeol Whang
Artificial Photosynthesis: Learning from Nature [Review]
ChemPhotoChem 10.1002/cptc.201700163

Jiwhan Kim, Hee-Eun Kim, Hyunjoo Lee
Single-Atom Catalysts of Precious Metals for Electrochemical Reactions [Minireview]
ChemSusChem 2018, vol. 11, p. 104

Ross J. Marshall, Ross S. Forgan
Postsynthetic Modification of Zirconium Metal-Organic Frameworks [Microreview]
Eur. J. Inorg. Chem. 2016, p. 4310

Davin Tan, Tomislav Friščić
Mechanochemistry for Organic Chemists: An Update [Microreview]
Eur. J. Org. Chem. 2018, p. 18

Deutscher Lebensmittelchemikertag 2016 in Freising-Weihenstephan [Vorträge]
Lebensmittelchemie 2017, vol. 71, p. 2

Meilensteine der Chemie 2018 [Bildung & Gesellschaft]
Nachr. Chem. 2018, vol. 66, p. 38

Katrin Sommer, Christina Toschka, Laura Schröder, Thomas Philipp Schröder, Henning Steff, Roland A. Fischer
Modellexperimente im Chemieunterricht. [Artikel]
CHEMKON 2017, vol. 24, p. 13

Catharina Goedecke
Why Does Iodine Turn Starch Blue?
ChemViews Magazine 2016

Most cited articles from each ChemPubSoc Europe, ACES, and GDCh journal



Shoujun Zhu, Qingnan Meng, Lei Wang, Junhu Zhang, Yubin Song, Han Jin, Kai Zhang, Hongchen Sun, Haiyu Wang, Bai Yang
Highly Photoluminescent Carbon Dots for Multicolor Patterning, Sensors, and Bioimaging
Angew. Chem. Int. Ed. 2013, vol. 52, pp. 3953–3957

Balayeshwanth R. Vummidi, Jawad Alzeer, Nathan W. Luedtke
Fluorescent Probes for G-Quadruplex Structures [Review]
ChemBioChem 2013, vol. 14, pp. 540–558

Zhi-Yuan Gu, Jihye Park, Aaron Raiff, Zhangwen Wei, Hong-Cai Zhou
Metal–Organic Frameworks as Biomimetic Catalysts [Minireview]
ChemCatChem 2014, vol. 6, pp. 67–75

Anthony J. Arduengo, Roland Krafczyk
Auf der Suche nach Stabilen Carbenen [Organische Chemie]
Chem. Unserer Zeit 1998, vol. 32, pp. 6–14

Marc Steinmetz, Stefan Grimme
Benchmark Study of the Performance of Density Functional Theory for Bond Activations with (Ni,Pd)-Based Transition-Metal Catalysts [Full Paper]
ChemistryOpen 2013, vol. 2, pp. 115–124

Philipp Scharf, Jens Müller
Nucleic Acids With Metal-Mediated Base Pairs and Their Applications [Review]
ChemPlusChem 2013, vol. 78, pp. 20–34

Philipp Kaiser, Rajabhau Bajirao Unde, Christoph Kern, Andreas Jess
Production of Liquid Hydrocarbons with CO2 as Carbon Source based on Reverse Water-Gas Shift and Fischer-Tropsch Synthesis [Research Article]
Chem. Ing. Tech. 2013, vol. 85, pp. 489–499

Xiaosi Zhou, Yu-Guo Guo
Highly Disordered Carbon as a Superior Anode Material for Room-Temperature Sodium-Ion Batteries [Communication]
ChemElectroChem 2014, vol. 1, pp. 83–86

Chuanxi Wang, Zhenzhu Xu, Chi Zhang
Polyethyleneimine-Functionalized Fluorescent Carbon Dots: Water Stability, pH Sensing, and Cellular Imaging [Full Paper]
ChemNanoMat 2015, vol. 1, pp. 122–127

Konggang Qu, Jiasi Wang, Jinsong Ren, Xiaogang Qu
Carbon Dots Prepared by Hydrothermal Treatment of Dopamine as an Effective Fluorescent Sensing Platform for the Label-Free Detection of Iron(III) Ions and Dopamine [Full Paper]
Chem. Eur. J. 2013, vol. 19, pp. 7243–7249

Yinuo Wu, Jun Wang, Fei Mao, Fuk Yee Kwong
Palladium-Catalyzed Cross-Dehydrogenative Functionalization of C(sp2)–H Bonds [Focus Review]
Chem. Asian J. 2014, vol. 9, pp. 26–47

Naohiko Yoshikai, Ye Wei
Synthesis of Pyrroles, Indoles, and Carbazoles through Transition-Metal-Catalyzed C–H Functionalization [Review]
Asian J. Org. Chem. 2013, vol. 2, pp. 466–478

Lluís Ballell, Robert H. Bates, Rob J. Young, Daniel Alvarez-Gomez, Emilio Alvarez-Ruiz, Vanessa Barroso, Delia Blanco, Benigno Crespo, Jaime Escribano, Rubén González, Sonia Lozano, Sophie Huss, Angel Santos-Villarejo, José Julio Martín-Plaza, Alfonso Mendoza, María José Rebollo-Lopez, Modesto Remuiñan-Blanco, José Luis Lavandera, Esther Pérez-Herran, Francisco Javier Gamo-Benito, José Francisco García-Bustos, David Barros, Julia P. Castro, Nicholas Cammack
Fueling Open-Source Drug Discovery: 177 Small-Molecule Leads against Tuberculosis [Full Paper]
ChemMedChem 2013, vol. 8, pp. 313–321

Peter Politzer, Jane S. Murray
Halogen Bonding: An Interim Discussion [Review]
ChemPhysChem 2013, vol. 14, pp. 278–294

Volker Hessel, Dana Kralisch, Norbert Kockmann, Timothy Noël, Qi Wang
Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry [Review]
ChemSusChem 2013, vol. 6, pp. 746–789

Helena J. Shepherd, Gábor Molnár, William Nicolazzi, Lionel Salmon, Azzedine Bousseksou
Spin Crossover at the Nanometre Scale [Microreview]
Eur. J. Inorg. Chem. 2013, pp. 653–661

Junichiro Yamaguchi, Kei Muto, Kenichiro Itami
Recent Progress in Nickel-Catalyzed Biaryl Coupling [Microreview]
Eur. J. Org. Chem. 2013, pp. 19–30

David Schweinfurth, Naina Deibel, Fritz Weisser, Biprajit Sarkar
Mit Klick zu neuen Liganden [Magazin]
Nachr. Chem. 2011, vol. 59, pp. 937–941
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