Chemical Development & Scale-Up in the Fine Chemical and Pharmaceutical Industries

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This three-day course, written and presented by process chemists from the pharmaceutical and fine chemical industry, provides a comprehensive overview of chemical process development. A logical investigative approach to all aspects of chemical development is described, with case studies from literature, conferences, and private communications. The multi-disciplinary nature of chemical development is emphasized, from the initial interaction with laboratory research scientists to the vital partnership with chemical engineers in the pilot plant and in the production environment. The lectures are interspersed with interactive problem sessions, enabling participants to share in the problem solving and troubleshooting typically experienced during chemical development.


  • Dr. John Knight
  • Dr. Will Watson


  • Synthetic Route Discovery
  • Costing of Chemical Processes
  • The Investigative Approach to Chemical Development
  • Solvent Effects
  • Statistical Methods of Optimisation
  • Analytical Issues
  • Work Up
  • Planning for Scale-Up
  • Appreciation of Chemical Engineering Principles
  • Crystallisation and Polymorphism
  • New and Emerging Technologies in Process R&D
  • Thermal Hazard Testing and Runaway Reactions
  • Effluent Minimisation and Control

Who Should Attend?

  • Young Chemists who have just started work in industry as development chemists
  • Organic Chemists/Medicinal Chemists in Research and Development who would like to gain an appreciation of development and scale up and who are perhaps contemplating moving into chemical development.
  • Development and Production Chemists in industry who would like to improve their efficiency and gain an insight into alternative approaches to chemical development.
  • Chemical Engineers who wish to understand a chemist’s approach to chemical development of batch processes. (Engineers would, however, need a good grounding in organic chemistry)
  • Students who are about to enter the industry and can obtain company sponsorship.
  • Experienced Chemists looking to refresh and/or augment their knowledge of chemical development
  • Analytical Chemists who wish to gain a broader appreciation of process chemistry
  • Managers who might benefit from a comprehensive and up to date overview of chemical development


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