Cavitand Sensor for Alcohol Detection

  • Author: ChemViews
  • Published Date: 18 April 2011
  • Source / Publisher: Angewandte Chemie International Edition/Wiley-VCH
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
thumbnail image: Cavitand Sensor for Alcohol Detection

The ability to sense and monitor different chemical species in the gas phase has applications that range from detecting environmental pollutants and hazardous chemicals, to disease diagnosis from volatiles present in breath. Most organic and polymer-based sensors detect analytes by polarity.

Enrico Dalcanale and co-workers, Università di Parma, Italy, have used an H-bonding approach to detecting short chain alcohols with a phosphonate cavitand. The alcohols H-bond to the P=O group of the cavitand, which induces a change in the fluorescence emission of the attached fluorophore. The cavitand has a strong preference for C1–C4 alcohols and is sufficiently selective to discriminate between alcohols on the basis of a single methylene unit difference.

This approach could allow the discrimination of analytes by chemical class, rather than by polarity.

Image: (c) Wiley-VCH

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