Microreactor Setup with Internal Recirculation

  • Author: Elmar Zimmermann
  • Published Date: 11 August 2013
  • Source / Publisher: Chemical Engineering & Technology/Wiley-VCH
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
thumbnail image: Microreactor Setup with Internal Recirculation

The Beckmann rearrangement of cyclohexanone oxime to ε-caprolactam is one of the most important chemical steps in the synthesis of this very important precursor of nylon-6. Generally, oleum, also known as fuming sulfuric acid, is used as catalyst for this rearrangement. Up until now, all published microreactor-type Beckmann rearrangement experiments with solutions of cyclohexanone oxime were performed in the once-through mode and/or internal recirculation was mimicked by adding the final product ε-caprolactam to the oleum.

Jaap C. Schouten and co-workers, Eindhoven University of Technology, The Netherlands, experimentally verified the Beckmann rearrangement of a solution of cyclohexanone oxime in cyclooctane with oleum in a microreactor with internal recirculation. The microreactor setup is comprised of combination of micromixers and microchannels. Two split-and-recombine micromixers were used for the mixing of ε-caprolactam in oleum with additional oleum and for the mixing of ε-caprolactam in oleum with solutions of cyclohexanone oxime in cyclooctane.

This method demonstrates the reliability of using microreactors with hazardous chemicals.

Article Views: 2565

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

Bookmark and Share

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission. more


ChemistryViews.org on Facebook

ChemistryViews.org on Twitter ChemistryViews.org on YouTube ChemistryViews.org on LinkedIn Sign up for our free newsletter

Magazine of Chemistry Europe (16 European Chemical Societies)published by Wiley-VCH