Carbohydrate Orientation

  • Author: Saskia Neubacher
  • Published Date: 07 September 2014
  • Source / Publisher: ChemistryOpen/Wiley-VCH
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
thumbnail image: Carbohydrate Orientation

Related Societies

Carbohydrate recognition is an important biological process that is essential for the communication between cells, such as cellular adhesion and recognition. A control of the spatial orientation of these carbohydrate units could potentially be used to modify this recognition event.

Thisbe Lindhorst and colleagues, University of Kiel, Germany, synthesized azobenzene glycosides with systematically varied structural properties using glycoside synthesis and the Mills reaction. The incorporation of an azobenzene moiety enables photoinduced E to Z isomerization leading to a different temporal orientation of the glycoside units. The photochromic properties of these different glycoconjugates were tested, and the results show that the anomeric linkage of a glycoside and the configuration of the 2-OH group can be crucial for the photoisomerization properties.


Article Views: 3548

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from, please contact us first for permission and consult our permission guidance prior to making your request

Follow on Facebook Follow on Twitter Follow on YouTube Follow on LinkedIn Follow on Instagram RSS Sign up for newsletters

Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH