In this issue, B. V. L. Potter et al. review inositols and their phosphates. What are the recent advances in their synthesis, biology, and medicine? In a Minireview, E. J. New et al. summarize research on reversible fluorescent probes for biological redox states. The Highlight deals with hierarchical self-assembly for nanomedicine (K. J. M. Bishop).

In the Communications section, R. Dronskowski et al. present ε-TiO, a novel stable polymorph of titanium monoxide. A. A. Deniz et al. describe the asymmetric modulation of protein order–disorder transitions by phosphorylation and partner binding. W. Yang and J. Sun succeeded in an organocatalytic enantioselective synthesis of 1,4-dioxanes and other oxa-heterocycles by oxetane desymmetrization.

• Angewandte Chemie 5/2016: Sweet Chemistry,
  Angew. Chem. Int. Ed. 2016, 55 (5).