Journal of Molecular Recognition

thumbnail image: Journal of Molecular Recognition
  • Editorial Board: MARC H. V. VAN REGENMORTEL, France
  • Published Date: 22 June 2010
  • Source / Publisher: John Wiley & Sons, Ltd.
  • Copyright: John Wiley & Sons, Ltd.

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Journal of Molecular Recognition (JMR, ISI Impact Factor 2011: 3.310) publishes original research papers and reviews describing molecular recognition phenomena in biology. Molecular recognition refers to the non-covalent specific interaction between two or more biological molecules exemplified by receptor-ligand, antigen-antibody, DNA-protein, sugar-lectin and many other interactions. Biomolecular interactions are studied both at structural level in terms of atomic coordinates and at functional level in terms of kinetic and equilibrium binding constants.

In recent years, these studies have been extended to multimacromolecular complexes and various molecular interaction networks as well as to cellular modules and organelles. The focus is on studies that aim to achieve a complete description of recognition sites in terms of structure, dynamics and activity.

JMR provides a forum for research in the field of quantitative biomolecular interaction analysis using biosensors and other solution or surface-mediated experimental techniques including microcalorimetry, atomic force microscopy and molecular imprinting. Since the understanding of molecular recognition at a microscopic level can be aided by theoretical approaches, including electrostatic analysis, molecular dynamics and free energy simulations, these aspects will also be covered. Submission of manuscripts related to the application of other instrumental methods, such as HPLC, LC-MS, CE-MS, NMR/MRI, PET and crystallography employed in the elucidation of the biophysical basis of the pathways of molecular recognition between interacting biological molecules are encouraged.

The design, synthesis and application of structural or topological mimics of naturally occurring molecules in the characterisation of molecular recognition processes represent a further aspect encompassed by JMR. These technologies in conjunction with site directed mutagenesis are providing new insights into the correlation between atomic structure and binding energy and pave the way to improved computer simulation, docking and molecular design of biologically active molecules. JMR also publishes articles on the applications of chemically and biologically generated molecular libraries and the creation of novel functions.

JMR publishes the best research presented at the following conferences: Affinity Meetings (organized by the International Society of Molecular Recognition ISMR), AFM BioMed Conferences and the International Conferences on Molecular Recognition (Aegean Conferences).

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Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH