Toxicity of Cr-Nanoparticles

  • Author: ChemistryViews
  • Published: 11 April 2011
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
  • Source / Publisher: Environmental Toxicology/Wiley Periodicals
thumbnail image: Toxicity of Cr-Nanoparticles

Nanoparticles are starting to be used in more and more applications. As their use increases, so does concern about their short- and long-term effects on health and the environment. Masanori Horie and colleagues, National Institute of Advanced Industrial Science and Technology, Japan, have compared Cr2O3 nanoparticles and fine particles in cell culture medium.

The fine Cr2O3 particles – currently used in industry as catalysts and pigments – were insoluble in the culture medium and were found to be non-toxic. The nanoparticles were shown to be soluble and released hexavalent chromium (K2Cr2O7), human carcinogen, into the medium. The nanoparticles induced oxidative stress and apoptosis on culture cells, meaning Cr2O3 nanoparticles show the potential for severe cytotoxicity.

Article Views: 3748

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from, please contact us first for permission. more

Follow on Facebook Follow on Twitter Follow on YouTube Follow on LinkedIn Follow on Instagram RSS Sign up for newsletters

Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH