Merck Accelerates Scale Up of Lipids for mRNA Covid-19 Vaccines

  • Author: ChemistryViews
  • Published: 26 May 2021
  • Copyright: Wiley-VCH GmbH
  • Associated Suppliers: Merck KGaA, Darmstadt, Germany
thumbnail image: Merck Accelerates Scale Up of Lipids for mRNA Covid-19 Vaccines

The genetic material of mRNA-based vaccines (e.g., COVID-19 vaccines) and therapeutics is packaged in lipids [1]. Merck launched a new, high-purity synthetic cholesterol product nine months ahead of schedule. Cholesterol is one component from which lipids are made.

There are both animal-derived and synthetic versions of cholesterol on the market. SAFC®, Merck's new synthetic cholesterol product, has high purity, scalability, and consistent quality. It is more than 99 % pure, offers high batch-to-batch consistency, and is scalable under commercial GMP. Merck is one of the few companies in the world capable of producing the volumes required to manufacture lipid nanoparticles and meet the quality requirements for mRNA therapeutics.

The launch of this new product follows the acquisition of AmpTec, a Hamburg, Germany-based mRNA contract development and manufacturing company. By combining AmpTec's PCR-based mRNA technology with Merck's expertise in lipid manufacturing, Merck can provide a truly integrated offering across the entire mRNA value chain.

Merck is collaborating with more than 50 companies to help them develop and produce Covid-19 vaccines and treatments by providing custom lipids as well as other key raw materials, processing equipment, and services for mRNA drug and vaccine manufacturing.


 

Also of Interest

 




 

Article Views: 2189

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission and consult our permission guidance prior to making your request

Follow on Facebook Follow on Twitter Follow on YouTube Follow on LinkedIn Follow on Instagram RSS Sign up for newsletters

Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH