Nickel Inversion

  • Author: David Bradley
  • Published: 15 March 2012
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
  • Source / Publisher: Chemical Communications/RSC Publishing
thumbnail image: Nickel Inversion

Researchers led by Takuya Kurahashi, Kyoto University, Japan, have developed what can be described as a formal inverse electron-demand Diels-Alder cycloaddition for the synthesis of highly substituted arenes. The team explains that the reaction can be attributed to the formation of an intermediate with the nickel ion, a seven-membered nickelacycle formed from a diene and an alkyne. They point out that activation of both olefins of the diene is essential for the cycloaddition reaction.

Until now, most reactions in this area of transition metal catalysis have used electron-rich dienes.

Article Views: 2663

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from, please contact us first for permission. more

CONNECT: on Facebook on Twitter on YouTube on LinkedIn Sign up for our free newsletter

Magazine of Chemistry Europe (16 European Chemical Societies)published by Wiley-VCH