Differences between the biochemistry of stem cells and mature heart and nerve cells have been revealed.

Gisbert Schneider and co-workers, Goethe-University, Frankfurt, Germany, report on target profile prediction to identify cross-activities of peroxisome proliferator-activated receptor (PPAR) and farnesoid X receptor (FXR).

Deracemization of mandelic acid to optically pure L-phenylglycine via a redox-neutral biocatalytic cascade.

Freya Klepsch and Gerhard F. Ecker, University of Vienna, Austria, highlight the Impact of the recent mouse P-glycoprotein structure for structure-based ligand design.