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Surface and Interface Analysis

The improvement in interfacial shear strength of wood fiber/epoxy composite by sizing with epoxy sizing agent containing MWCNTs

Published: 22 June 2018

Author(s): Runqin He, Qiuxiang Chang, Chunzheng Peng

This paper discloses a feasible and high efficient strategy for wood fiber treatment to introducing multi‐wall carbon nanotubes (MWCNTs) to the surface of wood fibers for the aim of improving the interfacial shear strength of wood fiber/epoxy composite. Briefly, a layer of MWCNT was deposited on wood fibers through sizing wood fibers with epoxy sizing agent containing amine‐treated MWCNTs (MWCNT‐PEI). The surface functional groups,...

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British Journal of Clinical Pharmacology

Gestational changes in buprenorphine exposure: A physiologically‐based pharmacokinetic analysis

Published: 21 June 2018

Author(s): Hongfei Zhang, Hari V. Kalluri, Jaime R. Bastian, Huijun Chen, Ali Alshabi, Steve N. Caritis, Raman Venkataramanan

Aims Buprenorphine (BUP) is approved by the US Food and Drug Administration for the treatment of opioid addiction. The current dosing regimen of BUP in pregnant women is based on recommendations designed for nonpregnant adults. However, physiological changes during pregnancy may alter BUP exposure and efficacy. The objectives of this study were to develop a physiologically‐based pharmacokinetic (PBPK) model...

British Journal of Clinical Pharmacology

The analgesic efficacy and pharmacokinetics of epidural oxycodone after gynaecological laparotomy: a randomized, double‐blind, double‐dummy comparison with intravenous administration

Published: 21 June 2018

Author(s): Panu Piirainen, Hannu Kokki, Heidi Hautajärvi, Veli‐Pekka Ranta, Merja Kokki

Aim The aim of the present study was to compare the analgesic efficacy of epidural and intravenous (i.v.) oxycodone at the same dose. Methods In this randomized, double‐blind, double‐dummy clinical trial, 30 women, aged 24–67 years, undergoing elective gynaecological laparotomy, were administrated either i.v. saline and epidural oxycodone...

British Journal of Clinical Pharmacology

Patient involvement is essential in identifying drug‐related problems

Published: 21 June 2018

Author(s): Heini Kari, Hanna Kortejärvi, Marja Airaksinen, Raisa Laaksonen

Aims The aim of this study is to evaluate how critical patient involvement is in pharmacist‐led clinical medication reviews and in identifying the most significant clinical drug‐related problems (DRPs). Methods Pharmacist‐led clinical medication reviews were conducted with 161 consenting patients aged ≥75 years with at least seven prescribed...

British Journal of Clinical Pharmacology

Genotype‐guided warfarin dosing vs . conventional dosing strategies: a systematic review and meta‐analysis of randomized controlled trials

Published: 21 June 2018

Author(s): Gary Tse, Mengqi Gong, Guangping Li, Sunny Hei Wong, William K. K. Wu, Wing Tak Wong, Leonardo Roever, Alex Pui Wai Lee, Gregory Y. H. Lip, Martin C. S. Wong, Tong Liu,

Aims Previous trials on the effectiveness of genotype‐guided warfarin dosing vs. conventional dosing have been inconclusive. We conducted a systematic review and meta‐analysis of randomized trials comparing genotype‐guided to conventional dosing strategies. Methods PubMed and the Cochrane Library were searched up to 23 October 2017. ...

British Journal of Clinical Pharmacology

Pharmacokinetics and safety of fluconazole and micafungin in neonates with systemic candidiasis: a randomized, open‐label clinical trial

Published: 21 June 2018

Author(s): S. Leroux, E. Jacqz‐Aigrain, V. Elie, F. Legrand, C. Barin‐Le Guellec, B. Aurich, V. Biran, B. Dusang, S. Goudjil, S. Coopman, R. Garcia Sanchez, W. Zhao, P. Manzoni,

Aims The pharmacokinetics (PK) of fluconazole and micafungin differ in neonates compared with children and adults. Dosing instructions in product labels appear to be inconsistent with the emerging scientific evidence. Limited information is available on the safety profile of these agents in neonates. Our objective was to study the population PK and safety of both drugs, randomly administered in neonates with...

British Journal of Pharmacology

Human monocyte transcriptional profiling identifies IL‐18 receptor accessory protein and lactoferrin as novel immune targets in hypertension

Published: 21 June 2018

Author(s): Matthew R Alexander, Allison E Norlander, Fernando Elijovich, Ravi V Atreya, Amadou Gaye, Juan S Gnecco, Cheryl L Laffer, Cristi L Galindo, Meena S Madhur

Background and Purpose Monocytes play a critical role in hypertension. The purpose of our study was to use an unbiased approach to determine whether hypertensive individuals on conventional therapy exhibit an altered monocyte gene expression profile and to perform validation studies of selected genes to identify novel therapeutic targets for hypertension. Experimental Approach ...

British Journal of Pharmacology

New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism

Published: 21 June 2018

Author(s): Elizabeth A Vecchio, Jo‐Anne Baltos, Anh T N Nguyen, Arthur Christopoulos, Paul J White, Lauren T May

Adenosine receptors are a family of GPCRs containing four subtypes (A1, A2A, A2B and A3 receptors), all of which bind the ubiquitous nucleoside adenosine. These receptors play an important role in physiology and pathophysiology and therefore represent attractive drug targets for a range of conditions. The theoretical framework surrounding drug action at adenosine receptors now extends beyond the notion of prototypical agonism and antagonism to...

Helvetica Chimica Acta

Fluorescent Nucleobase Analogues with Extended Pi Surfaces Stabilize DNA Duplexes Containing O ⁶ ‐Alkylguanine Adducts

Published: 21 June 2018

Author(s): Heidi A. Dahlmann, Florence D. Berger, Ryan W. Kung, Laura A. Wyss, Irina Gubler, Maureen McKeague, Stacey D. Wetmore, Shana J. Sturla

Chemical alkylation of DNA produces potentially toxic and mutagenic damage such as O6‐alkylguanine (O6‐alkylG) adducts. Non‐natural nucleoside analogues that pair with DNA adducts provide a potential basis for studying damaged DNA. Herein, we evaluated the base pairing properties of elongated nucleoside analogues containing napthalene‐derived tricyclic nucleobases as DNA adduct‐pairing nucleoside analogues in DNA hybridization probes. DNA duplex...

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Dynamic lateral organization of opioid receptors (kappa, mu _wt and mu _N40D ) in the plasma membrane at the nanoscale level

Published: 21 June 2018

Author(s): Maciej K. Rogacki, Ottavia Golfetto, Steven J. Tobin, Tianyi Li, Sunetra Biswas, Raphael Jorand, Huiying Zhang, Vlad Radoi, Yu Ming, Per Svenningsson, Daniel Ganjali, Devin L. Wakefield, Athanasios Sideris, Alexander R. Small, Lars Terenius, Tijana Jovanović‐Talisman, Vladana Vukojević

Opioid receptors are important pharmacological targets for the management of numerous medical conditions (eg, severe pain), but they are also the gateway to the development of deleterious side effects (eg, opiate addiction). Opioid receptor signaling cascades are well characterized. However, quantitative information regarding their lateral dynamics and nanoscale organization in the plasma membrane remains limited. Since these dynamic...

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Most-accessed articles from each ChemPubSoc Europe, ACES, and GDCh journal

March 2018


	Zhang Luo, Bing Liu Shape-Tunable Colloids from Structured Liquid Droplet Templates [Cover Picture] Angew. Chem. Int. Ed. 10.1002/anie.201802726

	Coline Jumeaux, Olov Wahlsten, Stephan Block, Eunjung Kim, Rona Chandrawati, Philip D. Howes, Fredrik Höök, Molly M. Stevens MicroRNA Detection by DNA-Mediated Liposome Fusion [Communication] ChemBioChem 2018, vol. 19, p. 434

	Isabela C. Man, Hai-Yan Su, Federico Calle-Vallejo, Heine A. Hansen, José I. Martínez, Nilay G. Inoglu, John Kitchin, Thomas F. Jaramillo, Jens K. Nørskov, Jan Rossmeisl Universality in Oxygen Evolution Electrocatalysis on Oxide Surfaces [Full Paper] ChemCatChem 2011, vol. 3, p. 1159

	Matthias Schäfer, Bernhard Hauck, Jochen Kuhn, Roland Ulber Analytik mit Licht - Das Smartphone-Photometer [Artikel] Chem. Unserer Zeit 2018, vol. 52, p. 52

	Balaram Mukhopadhyay, Rituparna Das Chemical O-Glycosylations: An Overview [Review] ChemistryOpen 2016, vol. 5, p. 401

	Hanshen Xin, Xike Gao Application of Azulene in Constructing Organic Optoelectronic Materials: New Tricks for an Old Dog [Minireview] ChemPlusChem 2017, vol. 82, p. 945

	Miaofang Chi, Harry M. Meyer, Zili Wu, Liangbo Liang, Peter V. Bonnesen, Dale K. Hensley, Rui Peng, Yang Song, Cheng Ma, Bobby G. Sumpter, Adam J. Rondinone High-Selectivity Electrochemical Conversion of CO₂ to Ethanol using a Copper Nanoparticle/N-Doped Graphene Electrode [Full Paper] ChemistrySelect 2016, vol. 1, p. 6055

	Hubert Rauscher, Kirsten Rasmussen, Birgit Sokull-Klüttgen Regulatory Aspects of Nanomaterials in the EU [Research Article] Chem. Ing. Tech. 2017, vol. 89, p. 224

	Abas Mohsenzadeh, Akram Zamani, Mohammad J. Taherzadeh Bioethylene Production from Ethanol: A Review and Techno-economical Evaluation [Review] ChemBioEng Rev. 2017, vol. 4, p. 75

	Robert A. W. Dryfe, Briony Setterfield-Price, Joanne Tory, František Hartl [M(CO)₄(2,2'-bipyridine)] (M=Cr, Mo, W) Complexes as Efficient Catalysts for Electrochemical Reduction of CO₂ at a Gold Electrode [Communication] ChemElectroChem 2015, vol. 2, p. 213

	Yinghui Xue, Qin Zhang, Tao Zhang, Lei Fu Black Phosphorus: Properties, Synthesis, and Applications in Energy Conversion and Storage [Focus Review] ChemNanoMat 2017, vol. 3, p. 352

	Maximilian Koy, Frederik Sandfort, Adrian Tlahuext-Aca, Linda Quach, Constantin G. Daniliuc, Frank Glorius Palladium-Catalyzed Decarboxylative Heck-Type Coupling of Activated Aliphatic Carboxylic Acids Enabled by Visible Light [Communication] Chem. Eur. J. 2018, vol. 24, p. 4552

	Jian Lv, Qi Zhang, Mao Cai, Yanfang Han, Sanzhong Luo Aromatic Aminocatalysis [Focus Review] Chem. Asian J. 2018, vol. 13, p. 740

	Hidetoshi Noda, Naoya Kumagai, Masakatsu Shibasaki Abstract [Focus Review] Asian J. Org. Chem. 10.1002/ajoc.201800013

	Albert J. Kooistra, Márton Vass, Ross McGuire, Rob Leurs, Iwan J. P. de Esch, Gert Vriend, Stefan Verhoeven, Chris de Graaf 3D-e-Chem: Structural Cheminformatics Workflows for Computer-Aided Drug Discovery [Full Paper] ChemMedChem 2018, vol. 13, p. 614

	Zhoufeng Bian, Sonali Das, Ming Hui Wai, Plaifa Hongmanorom, Sibudjing Kawi A Review on Bimetallic Nickel-Based Catalysts for CO₂ Reforming of Methane [Review] ChemPhysChem 2017, vol. 18, p. 3117

	Turkan Gamze Ulusoy Ghobadi, Amir Ghobadi, Ekmel Ozbay, Ferdi Karadas Strategies for Plasmonic Hot-Electron-Driven Photoelectrochemical Water Splitting [Review] ChemPhotoChem 2018, vol. 2, p. 161

	An-Na Cho, Nam-Gyu Park Impact of Interfacial Layers in Perovskite Solar Cells [Review] ChemSusChem 2017, vol. 10, p. 3687

	Jeffrey A. Rood, Sondra E. Hinman, Bruce C. Noll, Kenneth W. Henderson The Use of Halide-Substituted Anilines for the Formation of Magnesium Imides [Full Paper] Eur. J. Inorg. Chem. 2008, p. 3935

	D. B. Ramachary [Author Profile] Eur. J. Org. Chem. 10.1002/ejoc.201800182

	46. Deutscher Lebensmittelchemikertag 2017 in Würzburg [Tagung] Lebensmittelchemie 2018, vol. 72, p. 1

	Peter Chen Chemistry 4.0 [Leitartikel] Nachr. Chem. 2018, vol. 66, p. 203

	Ira Caspari, Gisela Weber-Peukert, Nicole Graulich Der Einsatz von Modellen zum Erkenntnisgewinn / Eine Unterrichtseinheit zur Förderung der Modellkompetenz im Kontext „Batterie“ unter explizitem Einbezug von Schülervorstellungen [Aus der Schule] CHEMKON 2018, vol. 25, p. 23

	Catharina Goedecke Why Does Iodine Turn Starch Blue? ChemViews Magazine 2016

Most cited articles from each ChemPubSoc Europe, ACES, and GDCh journal

2016


	Shoujun Zhu, Qingnan Meng, Lei Wang, Junhu Zhang, Yubin Song, Han Jin, Kai Zhang, Hongchen Sun, Haiyu Wang, Bai Yang Highly Photoluminescent Carbon Dots for Multicolor Patterning, Sensors, and Bioimaging Angew. Chem. Int. Ed. 2013, vol. 52, pp. 3953–3957

	Balayeshwanth R. Vummidi, Jawad Alzeer, Nathan W. Luedtke Fluorescent Probes for G-Quadruplex Structures [Review] ChemBioChem 2013, vol. 14, pp. 540–558

	Zhi-Yuan Gu, Jihye Park, Aaron Raiff, Zhangwen Wei, Hong-Cai Zhou Metal–Organic Frameworks as Biomimetic Catalysts [Minireview] ChemCatChem 2014, vol. 6, pp. 67–75

	Anthony J. Arduengo, Roland Krafczyk Auf der Suche nach Stabilen Carbenen [Organische Chemie] Chem. Unserer Zeit 1998, vol. 32, pp. 6–14

	Marc Steinmetz, Stefan Grimme Benchmark Study of the Performance of Density Functional Theory for Bond Activations with (Ni,Pd)-Based Transition-Metal Catalysts [Full Paper] ChemistryOpen 2013, vol. 2, pp. 115–124

	Philipp Scharf, Jens Müller Nucleic Acids With Metal-Mediated Base Pairs and Their Applications [Review] ChemPlusChem 2013, vol. 78, pp. 20–34

	Philipp Kaiser, Rajabhau?Bajirao Unde, Christoph Kern, Andreas Jess Production of Liquid Hydrocarbons with CO₂ as Carbon Source based on Reverse Water-Gas Shift and Fischer-Tropsch Synthesis [Research Article] Chem. Ing. Tech. 2013, vol. 85, pp. 489–499

	Xiaosi Zhou, Yu-Guo Guo Highly Disordered Carbon as a Superior Anode Material for Room-Temperature Sodium-Ion Batteries [Communication] ChemElectroChem 2014, vol. 1, pp. 83–86

	Chuanxi Wang, Zhenzhu Xu, Chi Zhang Polyethyleneimine-Functionalized Fluorescent Carbon Dots: Water Stability, pH Sensing, and Cellular Imaging [Full Paper] ChemNanoMat 2015, vol. 1, pp. 122–127

	Konggang Qu, Jiasi Wang, Jinsong Ren, Xiaogang Qu Carbon Dots Prepared by Hydrothermal Treatment of Dopamine as an Effective Fluorescent Sensing Platform for the Label-Free Detection of Iron(III) Ions and Dopamine [Full Paper] Chem. Eur. J. 2013, vol. 19, pp. 7243–7249

	Yinuo Wu, Jun Wang, Fei Mao, Fuk Yee Kwong Palladium-Catalyzed Cross-Dehydrogenative Functionalization of C(sp²)–H Bonds [Focus Review] Chem. Asian J. 2014, vol. 9, pp. 26–47

	Naohiko Yoshikai, Ye Wei Synthesis of Pyrroles, Indoles, and Carbazoles through Transition-Metal-Catalyzed C–H Functionalization [Review] Asian J. Org. Chem. 2013, vol. 2, pp. 466–478

	Lluís Ballell, Robert H. Bates, Rob J. Young, Daniel Alvarez-Gomez, Emilio Alvarez-Ruiz, Vanessa Barroso, Delia Blanco, Benigno Crespo, Jaime Escribano, Rubén González, Sonia Lozano, Sophie Huss, Angel Santos-Villarejo, José Julio Martín-Plaza, Alfonso Mendoza, María José Rebollo-Lopez, Modesto Remuiñan-Blanco, José Luis Lavandera, Esther Pérez-Herran, Francisco Javier Gamo-Benito, José Francisco García-Bustos, David Barros, Julia P. Castro, Nicholas Cammack Fueling Open-Source Drug Discovery: 177 Small-Molecule Leads against Tuberculosis [Full Paper] ChemMedChem 2013, vol. 8, pp. 313–321

	Peter Politzer, Jane S. Murray Halogen Bonding: An Interim Discussion [Review] ChemPhysChem 2013, vol. 14, pp. 278–294

	Volker Hessel, Dana Kralisch, Norbert Kockmann, Timothy Noël, Qi Wang Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry [Review] ChemSusChem 2013, vol. 6, pp. 746–789

	Helena J. Shepherd, Gábor Molnár, William Nicolazzi, Lionel Salmon, Azzedine Bousseksou Spin Crossover at the Nanometre Scale [Microreview] Eur. J. Inorg. Chem. 2013, pp. 653–661

	Junichiro Yamaguchi, Kei Muto, Kenichiro Itami Recent Progress in Nickel-Catalyzed Biaryl Coupling [Microreview] Eur. J. Org. Chem. 2013, pp. 19–30

	David Schweinfurth, Naina Deibel, Fritz Weisser, Biprajit Sarkar Mit Klick zu neuen Liganden [Magazin] Nachr. Chem. 2011, vol. 59, pp. 937–941