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Engineering in Life Sciences Engineering in Life Sciences

Enhancement of extracellular bispecific anti‐MUC1 nanobody expression in E. coli BL21 (DE3) by optimization of temperature and carbon sources through an autoinduction condition

Published: 25 May 2020

Author(s): Leila Rezaei, Seyed Abbas Shojaosadati, Leila Farahmand, Shima Moradi‐Kalbolandi

Abstract Escherichia coli is one of the most suitable hosts for production of antibodies and antibody fragments. Antibody fragment secretion to the culture medium improves product purity in cell culture and diminishes downstream costs. In this study, E. coli strain BL21 (DE3) harboring gene encoding bispecific anti‐MUC1 nanobody was selected, and the autoinduction methodology for expression of bispecific anti‐MUC1 nanobody was investigated. Due to the replacement of IPTG by lactose as inducer,...

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Chemistry - An Asian Journal

Hydrophilic Conjugated Materials for Photocatalytic Hydrogen Evolution

Published: 25 May 2020

Author(s): Yuanqing Bai, Zhicheng Hu, Jia‐Xing Jiang, Fei Huang

Abstract Photocatalytic hydrogen evolution is viewed as a promising green strategy to utilize the inexhaustible solar energy and provide clean hydrogen fuels with zero‐emission characteristic. The nature of semiconductor‐based photocatalysts is the key point to achieve efficient photocatalytic hydrogen evolution. Conjugated materials have been recently emerging as a novel class of photocatalysts for hydrogen evolution and photocatalytic reactions due to their electronic properties can be well...

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Bioorthogonal Phosphorogenic Rhenium(I) Polypyridine Sydnone Complexes for Specific Lysosome Labeling

Published: 25 May 2020

Author(s): Justin Shum, Pei‐Zhi Zhang, Lawrence Cho‐Cheung Lee, Kenneth Kam‐Wing Lo

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Chemistry - An Asian Journal

Metal Phthalocyanine‐Porphyrin‐based Conjugated Microporous Polymer‐derived Bifunctional Electrocatalysts for Zn‐Air Batteries

Published: 25 May 2020

Author(s): Yan Li, Xisheng Tao, Juncheng Wei, Xiaoling Lv, Heng‐Guo Wang

Abstract Conjugated microporous polymers (CMPs) as emerging porous materials with diverse structures and tunable building‐units have attracted much attention in the electrochemical field. Herein, we designed phthalocyanine‐porphyrin‐based conjugated microporous polymers as precursors for fabrication of Co, Fe, N tri‐doped graphene composites towards oxygen reduction and evolution reaction (ORR/OER). As expected, the elements cobalt and iron are well dispersed in graphene carbon and interact...

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Zeitschrift für anorganische und allgemeine Chemie

Assembly of Wells‐Dawson Polyoxometalate based Crystal Compound for Uric Acid Electrochemical Detection

Published: 25 May 2020

Author(s): Chang Liu, Mingqi Xu, Zenglong Tan, Si Li, Yu Wang, Yunliang Wang, Jingquan Sha

A new Wells‐Dawson polyoxometalates (POMs) based crystal supramolecular compound modified by flexible organic molecule bix, (H2bix)3(P2W18O62)·H2O (bixP2W18), [bix = 1,4‐bis(imidazol‐1‐ylmethyl)benzene], was synthesized, characterized and explored as electrochemical biosensor to detect uric acid (UA) for the first time. Under optimized conditions, the bixP2W18 based sensor shows acceptable analytical performances for UA in terms of good linearity in the concentration range from 2.5 × 10–7 to...

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International Journal of Applied Ceramic Technology

Novel design of microsphere adsorbent for efficient heavy metals adsorption

Published: 25 May 2020

Author(s): Lu Wang, Jingjing Liu, Yedong Rong, Shu Yan, Man Yu, Xinglin Li, Zhaoqing Wang, Tianhe Zhang, Jinlong Yang

Abstract The fabrication of high‐efficiency and low‐cost adsorbent for the wastewater treatment is a challenging task. In this study, a hollow sphere adsorbent was synthesized from solid waste coal gangue through a facile spray drying method and subsequent calcination. The structure of the synthesized coal gangue microsphere (CM) have been characterized by multimethods including X‐ray diffraction, scanning electron microscope, Fourier transform infrared, and others. The factors influencing the...

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Journal of Computational Chemistry

HCVpred: A web server for predicting the bioactivity of hepatitis C virus NS5B inhibitors

Published: 25 May 2020

Author(s): Aijaz Ahmad Malik, Chuleeporn Phanus‐umporn, Nalini Schaduangrat, Watshara Shoombuatong, Chartchalerm Isarankura‐Na‐Ayudhya, Chanin Nantasenamat

Abstract Hepatitis C virus (HCV) is one of the major causes of liver disease affecting an estimated 170 million people culminating in 300,000 deaths from cirrhosis or liver cancer. NS5B is one of three potential therapeutic targets against HCV (i.e., the other two being NS3/4A and NS5A) that is central to viral replication. In this study, we developed a classification structure–activity relationship (CSAR) model for identifying substructures giving rise to anti‐HCV activities among a set of...

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Proteins: Structure, Function, and Bioinformatics

Using machine learning to improve ensemble docking for drug discovery

Published: 25 May 2020

Author(s): Tanay Chandak, John P. Mayginnes, Howard Mayes, Chung F. Wong

Abstract Ensemble docking has provided an inexpensive method to account for receptor flexibility in molecular docking for virtual screening. Unfortunately, as there is no rigorous theory to connect the docking scores from multiple structures to measured activity, researchers have not yet come up with effective ways to use these scores to classify compounds into actives and inactives. This shortcoming has led to the decrease, rather than an increase in the performance of classifying compounds...

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Renewable RGO@CuI Nanocomposites for Redox Triggered Single Electron Transfer (SET) Reaction Under Aerobic and Anaerobic Conditions

Published: 25 May 2020

Author(s): Upasana Gulati, U. Chinna Rajesh, Diwan S. Rawat

Abstract Renewable mineral derived nanocatalysts are of special interest to accomplish green and sustainable goals with unique advantages over homogeneous catalysts such as recyclability, robustness, superior activity and minimum waste generation. Here, we synthesized reduced graphene oxide supported copper iodide (RGO@CuI) nanocomposites from renewable malachite mineral derived RGO@CuO precursor by treatment with NH2OH and KI in water. The characterization results reveal the role of RGO...

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Effects of Solid Electrolyte Interphase Components on the Reduction of LiFSI over Lithium Metal

Published: 25 May 2020

Author(s): Ethan P. Kamphaus, Stefany Angarita Gomez, Xueping Qin, Minhua Shao, Perla B. Balbuena

Abstract The use of a lithium metal anode still presents a challenging chemistry and engineering problem that holds back next generation lithium battery technology. One of the issues facing lithium metal is the presence of the solid electrolyte interphase (SEI) layer that forms on the electrode creating a variety of chemical species that change the properties of the electrode and is closely related to the formation and growth of lithium dendrites. In order to advance the scientific progress of...

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Most-accessed articles from each Chemistry Europe, ACES, and GDCh journal

January 2020


Hendrik Naatz, Bella B. Manshian, Carla Rios Luci, Vasiliki Tsikourkitoudi, Yiannis Deligiannakis, Johannes Birkenstock, Suman Pokhrel, Lutz Mädler, Stefaan J. Soenen
Model-Based Nanoengineered Pharmacokinetics of Iron-Doped Copper Oxide for Nanomedical Applications [Research Article]
Angew. Chem. Int. Ed. 2020, vol. 59, no. 5, p. 1828

Marc-André Kasper, Marcus Gerlach, Anselm F. L. Schneider, Christiane Groneberg, Philipp Ochtrop, Stefanie Boldt, Dominik Schumacher, Jonas Helma, Heinrich Leonhardt, Mathias Christmann, Christian P. R. Hackenberger
N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates [Full Paper]
ChemBioChem 2020, vol. 21, no. 1-2, p. 113

Michael Bowker
Methanol Synthesis from CO2 Hydrogenation [Minireview]
ChemCatChem 2019, vol. 11, no. 17, p. 4238

V. N. Danilevich, L. E. Petrovskaya, E. V. Grishin
A Highly Efficient Procedure for the Extraction of Soluble Proteins from Bacterial Cells with Mild Chaotropic Solutions [Research Article]
Chem. Eng. Technol. 2008, vol. 31, no. 6, p. 904

Dieter Wöhrle
Kunststoffe [Artikel]
Chem. Unserer Zeit 2019, vol. 53, no. 1, p. 50

Balaram Mukhopadhyay, Rituparna Das
Chemical O-Glycosylations: An Overview [Review]
ChemistryOpen 2016, vol. 5, no. 5, p. 401

Daewoo Han, Andrew J. Steckl
Coaxial Electrospinning Formation of Complex Polymer Fibers and their Applications [Review]
ChemPlusChem 2019, vol. 84, no. 10, p. 1453

Miaofang Chi, Harry M. Meyer, Zili Wu, Liangbo Liang, Peter V. Bonnesen, Dale K. Hensley, Rui Peng, Yang Song, Cheng Ma, Bobby G. Sumpter, Adam J. Rondinone
High-Selectivity Electrochemical Conversion of CO2 to Ethanol using a Copper Nanoparticle/N-Doped Graphene Electrode [Full Paper]
ChemistrySelect 2016, vol. 1, no. 19, p. 6055

Rüdiger-A. Eichel, Walter Leitner, Kurt Wagemann
Warum wir uns mit Power-to-X beschäftigen [Editorial]
Chem. Ing. Tech. 2020, vol. 92, no. 1-2, p. 3

Abas Mohsenzadeh, Akram Zamani, Mohammad J. Taherzadeh
Bioethylene Production from Ethanol: A Review and Techno-economical Evaluation [Review]
ChemBioEng Rev. 2017, vol. 4, no. 2, p. 75

Gerhard Hilt
Basic Strategies and Types of Applications in Organic Electrochemistry [Concept]
ChemElectroChem 2020, vol. 7, no. 2, p. 395

Claire M. Cobley
Introducing our Inaugural Early Career Advisory Board [Editorial]
ChemNanoMat 2020, vol. 6, no. 1, p. 4

Felix Blei, Sebastian Dörner, Janis Fricke, Florian Baldeweg, Felix Trottmann, Anna Komor, Florian Meyer, Christian Hertweck, Dirk Hoffmeister
Simultaneous Production of Psilocybin and a Cocktail of β-Carboline Monoamine Oxidase Inhibitors in “Magic” Mushrooms [Full Paper]
Chem. Eur. J. 2020, vol. 26, no. 3, p. 729

Sandip G. Agalave, Suleman R. Maujan, Vandana S. Pore
Click Chemistry: 1,2,3‐Triazoles as Pharmacophores [Focus Review]
Chem. Asian J. 2011, vol. 6, no. 10, p. 2696

Arun K. Sinha, Danish Equbal
Thiol−Ene Reaction: Synthetic Aspects and Mechanistic Studies of an Anti-Markovnikov-Selective Hydrothiolation of Olefins [Focus Review]
Asian J. Org. Chem. 2019, vol. 8, no. 1, p. 32

Thomas H. Pillow, Pragya Adhikari, Robert A. Blake, Jinhua Chen, Geoffrey Del Rosario, Gauri Deshmukh, Isabel Figueroa, Karen E. Gascoigne, Amrita V. Kamath, Susan Kaufman, Tracy Kleinheinz, Katherine R. Kozak, Brandon Latifi, Douglas D. Leipold, Chun Sing Li, Ruina Li, Melinda M. Mulvihill, Aimee O'Donohue, Rebecca K. Rowntree, Jack D. Sadowsky, John Wai, Xinxin Wang, Cong Wu, Zijin Xu, Hui Yao, Shang-Fan Yu, Donglu Zhang, Richard Zang, Hongyan Zhang, Hao Zhou, Xiaoyu Zhu, Peter S. Dragovich
Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity [Full Paper]
ChemMedChem 2020, vol. 15, no. 1, p. 17

Vitali Tugarinov, Theodoros K. Karamanos, Alberto Ceccon, G. Marius Clore
Optimized NMR Experiments for the Isolation of I=1/2 Manifold Transitions in Methyl Groups of Proteins [Communication]
ChemPhysChem 2020, vol. 21, no. 1, p. 13

Hiroki Tanaka, Yoshihisa Inoue, Tadashi Mori
Circularly Polarized Luminescence and Circular Dichroisms in Small Organic Molecules: Correlation between Excitation and Emission Dissymmetry Factors [Review]
ChemPhotoChem 2018, vol. 2, no. 5, p. 386

Kassem Beydoun, Jürgen Klankermayer
Efficient Plastic Waste Recycling to Value-Added Products by Integrated Biomass Processing [Communication]
ChemSusChem 2020, vol. 13, no. 3, p. 488

Stephen A. Matlin, Goverdhan Mehta, Henning Hopf, Alain Krief
The Periodic Table of the Chemical Elements and Sustainable Development [Essay]
Eur. J. Inorg. Chem. 2019, p. 4170

Luca Capaldo, Davide Ravelli
Hydrogen Atom Transfer (HAT): A Versatile Strategy for Substrate Activation in Photocatalyzed Organic Synthesis [Microreview]
Eur. J. Org. Chem. 2017, p. 2056

Cover Picture Lebensmittelchemie 6/2019 [Cover Picture]
Lebensmittelchemie 2019, vol. 73, no. 6

Christian Hering-Junghans, Christian Sindlinger
Trendbericht Anorganische Chemie: Hauptgruppen [Wissenschaft + Forschung]
Nachr. Chem. 2020, vol. 68, no. 1, p. 50

Jana Novotny, Corina Wagner, Marco Oetken
Titelbild: Elektrochemisch aktive Polymere am Beispiel Polypyrrol: Modellsystem einer künstlichen Synapse Ein elektrochemischer Alleskönner - Teil 2 (CHEMKON 8/2019) [Titelbild]
CHEMKON 2019, vol. 26, no. 8, p. 331

Meng Cheng, Ramasubramonian Deivanayagam, Reza Shahbazian-Yassar
3D Printing of Electrochemical Energy Storage Devices: A Review of Printing Techniques and Electrode/Electrolyte Architectures [Review]
Batteries & Supercaps 2020, vol. 3, no. 2, p. 130

Catharina Goedecke
Why Does Iodine Turn Starch Blue?
ChemViews Magazine 2016

Most cited articles from Chemistry Europe, ACES, and GDCh journals

Articles on this list are the most frequently cited ones among those published in 2017 or 2018 according to Web of Science. They have contributed the most to the journal's impact factor in 2019.


Yuanjun Chen, Shufang Ji, Yanggang Wang, Juncai Dong, Wenxing Chen, Zhi Li, Rongan Shen, Lirong Zheng, Zhongbin Zhuang, Dingsheng Wang, Yadong Li
Isolated Single Iron Atoms Anchored on N-Doped Porous Carbon as an Efficient Electrocatalyst for the Oxygen Reduction Reaction [Communication]
Angew. Chem. Int. Ed. 2017, vol. 56, pp. 6937–6941

Lik Hang Yuen, Raphael M. Franzini
Achievements, Challenges, and Opportunities in DNA-Encoded Library Research: An Academic Point of View [Minireview]
ChemBioChem 2017, vol. 18, pp. 829–836

Konstantinos C. Christoforidis, Paolo Fornasiero
Photocatalytic Hydrogen Production: A Rift into the Future Energy Supply [Review]
ChemCatChem 2017, vol. 9, pp. 1523–1544

Massimo Baroncini, Lorenzo Casimiro, Christiaan de Vet, Jessica Groppi, Serena Silvi, Alberto Credi
Making and Operating Molecular Machines: A Multidisciplinary Challenge [Minireview]
ChemistryOpen 2018, vol. 7, pp. 169–179

Hanshen Xin, Xike Gao
Application of Azulene in Constructing Organic Optoelectronic Materials: New Tricks for an Old Dog [Minireview]
ChemPlusChem 2017, vol. 82, pp. 945–956

Hojat Veisi, Mozhgan Pirhayati, Ali Kakanejadifard, Pourya Mohammadi, Mohammad Reza Abdi, Javad Gholami, Saba Hemmati
In Situ Green Synthesis of Pd Nanoparticles on Tannic Acid-Modified Magnetite Nanoparticles as a Green Reductant and Stabilizer Agent: Its Application as a Recyclable Nanocatalyst (Fe3O4@TA/Pd) for Reduction of 4-Nitrophenol and Suzuki Reactions [Full Paper]
ChemistrySelect 2018, vol. 3, pp. 1820–1826

Tingting Liu, Lisi Xie, Jianhui Yang, Rongmei Kong, Gu Du, Abdullah M. Asiri, Xuping Sun, Liang Chen
Self-Standing CoP Nanosheets Array: A Three-Dimensional Bifunctional Catalyst Electrode for Overall Water Splitting in both Neutral and Alkaline Media [Communication]
ChemElectroChem 2017, vol. 4, pp. 1840–1845

Ruibin Wang, Liheng Chen, J.Y. Zhu, Rendang Yang
Tailored and Integrated Production of Carboxylated Cellulose Nanocrystals (CNC) with Nanofibrils (CNF) through Maleic Acid Hydrolysis [Full Paper]
ChemNanoMat 2017, vol. 3, pp. 328–335

Chengwei Liu, Michal Szostak
Twisted Amides: From Obscurity to Broadly Useful Transition-Metal-Catalyzed Reactions by N−C Amide Bond Activation [Minireview]
Chem. Eur. J. 2017, vol. 23, pp. 7157–7173

Jian Shu, Dianping Tang
Current Advances in Quantum-Dots-Based Photoelectrochemical Immunoassays [Focus Review]
Chem. Asian J. 2017, vol. 12, pp. 2780–2789

Jian Rong, Chuanfa Ni, Jinbo Hu
Metal-Catalyzed Direct Difluoromethylation Reactions [Focus Review]
Asian J. Org. Chem. 2017, vol. 6, pp. 139–152

Juan Alberto Sirvent, Ulrich Lücking
Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates [Full Paper]
ChemMedChem 2017, vol. 12, pp. 487–501

Grzegorz Greczynski, Lars Hultman
C 1s Peak of Adventitious Carbon Aligns to the Vacuum Level: Dire Consequences for Material's Bonding Assignment by Photoelectron Spectroscopy [Communication]
ChemPhysChem 2017, vol. 18, pp. 1507–1512

Jia-Rong Chen, Dong-Mei Yan, Qiang Wei, Wen-Jing Xiao
Photocascade Catalysis: A New Strategy for Cascade Reactions [Concept]
ChemPhotoChem 2017, vol. 1, pp. 148–158

Zhiming Pan, Yun Zheng, Fangsong Guo, Pingping Niu, Xinchen Wang
Decorating CoP and Pt Nanoparticles on Graphitic Carbon Nitride Nanosheets to Promote Overall Water Splitting by Conjugated Polymers [Communication]
ChemSusChem 2017, vol. 10, pp. 87–90

Enzo Alessio
Thirty Years of the Drug Candidate NAMI-A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective [Microreview]
Eur. J. Inorg. Chem. 2017, pp. 1549–1560

Marcel Garbe, Kathrin Junge, Matthias Beller
Homogeneous Catalysis by Manganese-Based Pincer Complexes [Microreview]
Eur. J. Org. Chem. 2017, pp. 4344–4362

Qian Sun, Kah Chun Lau, Dongsheng Geng, Xiangbo Meng
Atomic and Molecular Layer Deposition for Superior Lithium-Sulfur Batteries: Strategies, Performance, and Mechanisms [Review]
Batteries Supercaps 2018, vol. 1, pp. 41–68

Hojat Veisi, Mozhgan Pirhayati, Ali Kakanejadifard, Pourya Mohammadi, Mohammad Reza Abdi, Javad Gholami, Saba Hemmati
In Situ Green Synthesis of Pd Nanoparticles on Tannic Acid-Modified Magnetite Nanoparticles as a Green Reductant and Stabilizer Agent: Its Application as a Recyclable Nanocatalyst (Fe3O4@TA/Pd) for Reduction of 4-Nitrophenol and Suzuki Reactions [Full Paper]
ChemistrySelect 2018, vol. 3, pp. 1820–1826

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Magazine of Chemistry Europe (16 European Chemical Societies)published by Wiley-VCH