2012 Trends in Organic Chemistry

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  • Author: ChemViews/GDCh
  • Published Date: 14 March 2013
  • Source / Publisher: Nachrichten aus der Chemie/GDCh
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
thumbnail image: 2012 Trends in Organic Chemistry

Nachrichten aus der Chemie (the membership magazine of the GDCh) annually publishes trend reports in which authors spot and compile an overview of inspiring work and recent trends in the most important chemical disciplines.


ChemViews gives you an overview of the latest trend report, its authors and the literature collected.


Trends in Organic Chemistry 2012

S. Bräse et al.

  • Highlights of the year
    Graphene — nanostructures from DNA building blocks — tuberculosis diagnostics — fluorination — pyrrolysine — and structural biology by NMR.


► Full article (in German):

All 2012 trend reports on ChemViews


Authors


The organic chemistry trend report 2012 had 29 authors, whose names can be found in the full article. Stefan Bräse, Institute of Organic Chemistry, Karlsruher Institute of Technology (KIT), was the coordinator of the report.

Stefan BräseSince 2001, Stefan Bräse has been a Professor of Organic Chemistry, first in Bonn, and then in Karlsruhe from 2003. He studied chemistry at the University of Göttingen, Germany, with Armin de Meijere, was a postdoctoral fellow in Uppsala, Sweden, with Jan Bäckvall and in La Jolla, USA, with K.C. Nicolaou, and became a professor at the RWTH Aachen, Germany, under the supervision of Dieter Enders.

His research interests include solid-phase synthesis, asymmetric catalysis, and the total synthesis of natural products.

Since 2005, he has coordinated the Organic Chemistry trend reports.




References

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Liquid Crystals

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Photochemistry

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Organic Dyes

38) W. Shi, X. Li, H. Ma, Angew. Chem. 2012, 124, 6538–6541. DOI: 10.1002/ange.201202533; Angew. Chem. Int. Ed. 2012, 51, 6432–6435. DOI: 10.1002/anie.201202533
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Heterocycles

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Green Chemistry

52) M. Peters, B. Köhler, W. Kuckshinrichs, W. Leitner, P. Markewitz, T. E. Müller, ChemSusChem 2011, 4, 1216–1240. DOI: 10.1002/cssc.201000447
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59) M. Rose, R. Palkovits, ChemSusChem 2011, 5, 167–176. DOI: 10.1002/cssc.201100580


Base and Fine Chemicals

60) M. Shiramizu F. D. Toste, Angew. Chem. 2012, 124, 8206–8210. DOI: 10.1002/ange.201203877; Angew. Chem. Int. Ed. 2012, 51, 8082–8086. DOI: 10.1002/anie.201203877
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62) A. Zanardi, M. A. Novikov, E. Martin, J. Benet-Buchholz, V. V. Grushin, J. Am. Chem. Soc. 2011, 133, 20901. DOI: 10.1021/ja2081026
63) K. Radkowski, B. Sundararaju, A. Fürstner, Angew. Chem. 2013, 125, 373–378. DOI: 10.1002/ange.201205946; Angew. Chem. Int. Ed. 2013, 52, 355–360. DOI: 10.1002/anie.201205946


Organometallics: Structures and Mechanisms

64) a) I. N. Michaelides, D. J. Dixon, Angew. Chem. 2013, 125, 836–838. DOI: 10.1002/ange.201208120; b) D. Schleyer, H. G. Niessen, J. Bargon, New. J. Chem. 2001, 25, 423–426. DOI: 10.1039/b007201j
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66) a) C. Cheng, M. Brookhart, J. Am. Chem. Soc. 2012, 134, 11304–11307. DOI: 10.1021/ja304547s; b) S. Park, B. G. Kim, I. Göttker-Schnetmann, M. Brookhart, ACS Catal. 2012, 2, 307–316. DOI: 10.1021/cs200629t


Computational Organic Chemistry

67) S. N. Steinmann, C. Corminboeuf, J. Chem. Theory Comput. 2011, 7, 3567. DOI:10.1021/ct200602x
68) F. Malberg, A. S. Pensado, B. Kirchner, Phys. Chem. Chem. Phys. 2012, 14, 12079. DOI: 10.1039/c2cp41878a
69) K. Schwing, H. Fricke, K. Bartl, J. Polkowska, T. Schrader, M. Gerhards, ChemPhysChem 2012, 13, 1576. DOI: 10.1002/cphc.201100805
70) H. Arp, J. Baumgartner, C. Marschner, P. Zark, T. Müller, J. Am. Chem. Soc. 2012, 134, 6409. DOI: 10.1021/ja300654t
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75) S. Grimme, WIREs Comput. Mol. Sci. 2011, 1, 211. DOI: 10.1002/wcms.30
76) R. Lonsdale, J. N. Harvey, A. J. Mulholland, J. Chem. Theory Comput. 2012, 8, 4637. DOI: 10.1021/ct300329h
77) X. S. Bogle, D. A. Singleton, Org. Lett. 2012, 14, 2528. DOI: 10.1021/ol300817a
78) O. M. Gonzalez-James, E. E. Kwan, D. A. Singleton, J. Am. Chem. Soc. 2012, 134, 1914. DOI: 10.1021/ja208779k
79) R. Gordillo, K. N. Houk, J. Am. Chem. Soc. 2006, 128, 3543. DOI: 10.1021/ja0525859v


Natural Products

80) J. B. Biggins, M. A. Ternei, S. F. Brady, J. Am. Chem. Soc. 2012, 134, 13192–13195. DOI: 10.1021/ja3052156
81) K. Graupner, K. Scherlach, T. Bretschneider, G. Lackner, M. Roth, H. Gross, C. Hertweck, Angew. Chem. 2012, 124, 13350–13354. DOI: 10.1002/ange.201206658; Angew. Chem. Int. Ed. 2012, 51, 13173–13177. DOI: 10.1002/anie.201206658
82) D. Poth, K. C. Wollenberg, M. Vences, S. Schulz, Angew. Chem. 2012, 124, 2229–2232. DOI: 10.1002/ange.201106592; Angew. Chem. Int. Ed. 2012, 51, 2187–2190. DOI: 10.1002/anie.201106592
83) P.-M. Allard, M.-T. Martin, M.-E. Tran Huu Dau, P. Leyssen, F. Gueritte, M. Litaudon, Org. Lett. 2012, 14, 342–345. DOI: 10.1021/ol2030907
84) J. Sikorska, A. M. Hau, C. Anklin, S. Parker-Nance, M. T. Davies-Coleman, J. E. Ishmael, K. L. McPhail, J. Org. Chem. 2012, 77, 6066–6075. DOI: 10.1021/jo3008622
85) Y. Hamamoto, K. Tachibana, P. T. Holland, F. Shi, V. Beuzenberg, Y. Itoh, M. Satake, J. Am. Chem. Soc. 2012, 134, 4963–4968. DOI: 10.1021/ja212116q
86) S.-X. Huang, X.-J. Wang, Y. Yan, J.-D. Wang, J. Zhang, C.-X. Liu, W.-S. Xiang, B. Shen, Org. Lett. 2012, 14, 1254–1257. DOI: 10.1021/ol300074d


Natural Products: Total Synthesis

87) J. Willwacher, N. Kausch-Busies, A. Fürstner, Angew. Chem. 2012, 124, 12207–12212. DOI: 10.1002/ange.201206670; Angew. Chem. Int. Ed. 2012, 51, 12041–12046. DOI: 10.1002/anie.201206670
88) K. Lehr, R. Mariz, L. Leseurre, B. Gabor, A. Fürstner, Angew. Chem. 2011, 123, 11575–11579. DOI: 10.1002/ange.201106117; Angew. Chem. Int. Ed. 2011, 50, 11373–11377. DOI: 10.1002/anie.201106117
89) M. E. Weiss, E. E. M. Carreira, Angew. Chem. 2011, 123, 11703–11707. DOI: 10.1002/ange.201104681; Angew. Chem. Int. Ed. 2012, 50, 11125. DOI: 10.1002/anie.201104681
90) A. Y. Hong, B. M. Stoltz, Angew. Chem. 2012, 124, 9812–9816. DOI: 10.1002/ange.201205276; Angew. Chem. Int. Ed. 2012, 51, 9674–9878. DOI: 10.1002/anie.201205276
91) J. T. Mohr, D. C. Behenna, A. M. Harned, B. M. Stoltz, Angew. Chem. 2005, 117, 7084–7087. DOI: 10.1002/ange.200502018; Angew. Chem. Int. Ed. 2005, 44, 6924–6927. DOI: 10.1002/anie.200502018
92) A. Y. Hong, M. R. Krout, T. Jensen, N. B. Bennett, A. M. Harned, B. M. Stoltz, Angew. Chem. 2011, 123, 2808–2812. DOI: 10.1002/ange.201007814; Angew. Chem. Int. Ed. 2011, 50, 2756. DOI: 10.1002/anie.201007814


Medicinal Chemistry

93) P. M. Barrett, A. Alagely, E. J. Topol, Hum. Mol. Gen. 2012, 21(R1), R66–R71. DOI: 10.1093/hmg/dds345
94) K. J. Moloney, J. U. Mercado, W. H. Ludlam, M. R. Mayberg, Exp. Rev. Endocrin. Metab. 2012, 7, 491–502. DOI: 10.1586/eem.12.49
95) K. Vaddi, N. J. Sarlis, V. Gupta, Exp. Opin. Pharmacother. 2012, 13, 2397–2407. DOI: 10.1517/14656566.2012.732998


Solid Phase Synthesis

96) J. J. Marineau, M. L. Snapper, ACS Comb. Sci. 2012, 14, 343–346. DOI: 10.1021/co2002069
97) A. La-Venia, S. A. Testero, M. P. Mischne, E. G. Mata, Org. Biomol. Chem. 2012, 10, 2514–2517. DOI: 10.1039/c2ob06881h
98) K. Knepper, S. Vanderheiden, S. Bräse, Beilstein J. Org. Chem. 2012, 8, 1191–1199. DOI: 10.3762/bjoc.8.132
99) M. Bru, S. P. Kotkar, N. Kar, M. Köhn, Chem. Sci. 2012, 3, 1893–1902. DOI: 10.1039/c2sc01061e
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