First Total Synthesis of Thiamyxins A–C and E
Potent class of RNA-virus-inhibiting (cyclo)depsipeptides
New Vaccine Concept against SARS-CoV-2 Successful in Animals
Vaccine based on a modified "single-cycle" virus that is incapable of replication
Hydrogen Sulfide in Cancer Treatment
Gas-releasing adjuvant improves efficacy of photothermal therapy against cancer
1,3‐Oxazoles as Anticancer Compounds
5-Sulfinyl(sulfonyl)-4-arylsulfonyl-substituted 1,3-oxazoles show promising activity
Clarity with Tiny Drug Crystals
Elusive structure of the antihistamine Levocetirizine determined by electron diffraction
Gold-Catalyzed Reaction Gives Antitumor-Active Spirocyclic Oxindoles
Formal cycloaddition reaction of terminal alkynes or ynamides with isatin-derived ketimines
Phosphine Oxide-Substituted Cyclam Ligand Synthesized
Ligand with high selectivity for Cu(II) over competing divalent cations
Angewandte Chemie 22/2023: Combinations
Overview of the latest issue of Angewandte Chemie
Liver-Targeted Nanoparticles for Treating Type 2 Diabetes
Drug-loaded reactive oxygen species (ROS) scavengers could restore insulin sensitivity
Trace Analysis of Blood Samples
Fluorescence probe and autofluorescence quencher in one
Drug Nanoparticles for the Treatment of Multidrug-Resistant Tuberculosis
Lipophilic antibiotics prepared as high-dose, amorphous nanoparticles for inhalation therapy
Most Accessed Articles: April 2023
Highlights from Chemistry Europe, ACES, and GDCh journals
Angewandte Chemie 21/2023: Structure and Performance
Overview of the latest issue of Angewandte Chemie
Johan Elf Awarded the Norblad-Ekstrand Medal
Physical chemistry professor from Uppsala University, Sweden, honored for his pioneering work in characterizing single molecules within the living cell
Copper(I) Complexes as Dual Anticancer and Antiparasitic Agents
Family of Cu(I) complexes with combinations of two phosphane ligands and two bioactive thiosemicarbazone derivatives
New Synthesis Route for Ketoprofen
Five-step synthesis starting from cyclohexanone with 44 % overall yield
Cyclic Analogue of the Analgesic Ziconotide Shows Improved Stability
Chemo-enzymatic approach used to generate cyclized analogues of peptides
Dental Restoration Materials
Let's take a closer look at the chemistry behind fixing our smiles
Better Cryoprotection for Red Blood Cells
Ultra-thin metal–organic layers prevent ice crystal formation