The Magazine of Chemistry Europe

A second-generation Smoothened (Smo) antagonist has shown excellent efficacy in rodent tumor models

Introduction of a sulfoximine group into anticancer candidates shows that sometimes sticking to the unconventional pays off

Sipholenol analogues revealed as novel scaffolds for drugs that inhibit breast cancer cell migration and invasion

Investigation of π-stacking interactions of protein amides could improve rational drug design

Open-source compound library at GSK identifies 177 small-molecule leads for anti-tuberculois (TB) research

Development and characterization of new peptidomimetic inhibitors of the West Nile virus NS2B-NS3 protease

Butyltin(IV) benzoates show inhibition of thioredoxin reductase, interactions with proteins, and tumor cell growth inhibition

Structure–activity relationships of non-steroidal antagonist series identifies BAY 94-8862 as a potential treatment for chronic heart failure

Series of biphenyl α-D-mannosides could prevent and treat urinary tract infections (UTIs) by blocking bacterial adhesion to host cells

Miniaturized high-throughput screening assays could help identify a prophylactic strategy against liver-stage malaria