Screening existing library of antagonists for binding affinity toward CD22 identifies new potential treatments for B-cell lymphomas

Screening existing library of antagonists for binding affinity toward CD22 identifies new potential treatments for B-cell lymphomas
A pharmacologically active antagonist of the two-pore-domain potassium ion channel could help treat depression
Hybrid lipoic acid derivatives attack prion disease on multiple fronts suggesting possible targets for treatment
Click chemistry can be used for the efficient labeling of (bio)molecules with 99mTc
Anti-malarial agents, artemisinins, undergo both one-electron transfer and two-electron reduction, with biological consequences
Resorcylic acid lactone (RAL) representing a unique pharmacophore was edited to improve the properties and diversify the scaffold.
Exploring the RPRL motif of apelin-13 through molecular simulation and biological evaluation of cyclic peptide analogues