Self-Healing Biomaterial

  • ChemPubSoc Europe Logo
  • Author: Andrei Dragan
  • Published Date: 24 April 2017
  • Source / Publisher: Chemistry - An Asian Journal/Wiley-VCH
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
thumbnail image: Self-Healing Biomaterial

Self-assembled soft materials such as supramolecular hydrogels have shown great promise in biomedical applications such as tissue engineering, cell therapy, and drug delivery. Their soft nature makes them biocompatible; however, it also means that they are not robust enough for most practical applications.

Kimoon Kim and colleagues, Institute for Basic Science and Pohang University of Science and Technology (POSTECH), South Korea, have prepared a supramolecular hydrogel which is able to ‘self-heal’ after it is damaged. The hydrogel is made by mixing two simple starting materials, which were both synthesized by one-step reactions from commercially available compounds (pictured): Guest (adamantylamine)-anchored hydrophilic polymers were stitched together using a host molecule (nor-seco-cucurbit[10]uril) that acts as a supramolecular crosslinker by accommodating two guest molecules in its cavity.

Because of the dynamic and reversible nature of the host–guest interaction, the hydrogel recovers its mechanical properties to near those of the pristine material, even after multiple damage–healing cycles, therefore, showing potential as a promising biomaterial with a prolonged lifetime.


 

Article Views: 939

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

Bookmark and Share

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission. more


CONNECT:

ChemistryViews.org on Facebook

ChemistryViews.org on Twitter ChemistryViews.org on YouTube ChemistryViews.org on LinkedIn Sign up for our free newsletter


A product of ChemPubSoc Europe (16 European Chemical Societies)and Wiley-VCH