In this issue, U. Rosenthal reviews reactions of Group 4 metallocene bis(trimethylsilyl)acetylene complexes with nitriles and isonitriles. How can they be applied in syntheses? In a Minireview, L. Ackermann et al. discuss late-stage peptide diversification by position-selective C–H activation. The Highlight addresses the question whether Meisenheimer complexes in SNAr reactions are intermediates or transition states (A. J. J. Lennox). S. A. Matlin et al. share a Viewpoint on equality, diversity, and inclusion in the chemical sciences.
In the Communications section, F. Göricke and C. Schneider present a palladium-catalyzed enantioselective addition of chiral metal enolates to in situ generated ortho-quinone methides (see picture). A. Robert et al. found that magnetite Fe3O4 has no intrinsic peroxidase activity and is probably not involved in Alzheimer’s oxidative stress. H. Cheng et al. used palladium phosphide as a stable and efficient electrocatalyst for overall water splitting.
- Angewandte Chemie 45/2018: Versatility,
Angew. Chem. Int. Ed. 2018, 57 (45).