Water-Soluble Self-Assembly with Pillar[n]arene Homologues

  • Author: Chemistry – An Asian Journal
  • Published Date: 15 January 2019
  • Source / Publisher: Chemistry – An Asian Journal/Wiley-VCH
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
thumbnail image: Water-Soluble Self-Assembly with Pillar[<i>n</i>]arene Homologues

Self-assembly is an important phenomenon in chemistry, biology, and materials science. Researchers are looking for tunable and versatile self-assembly systems. Self-assembly systems in water are particularly interesting because they could provide insights into biological processes.

Macrocyclic hosts such as cyclodextrins, calix[n]arenes, cucurbit[n]urils, pillar[n]arenes or PA[n]s, have been used to mediate self‐assembly of guests. By selecting proper host‐guest systems, tunable nanoscale architectures can be obtained.

Da Ma and colleagues, Fudan University, Shanghai, China, have studied tunable self-assembly systems in water. They used water-soluble pillar[n]arene homologues with different sizes (n = 5–7) as host and bipyridinium‐azobenzene guests. Pillar[n]arenes are a type of macrocyclic host molecules which can serve as artificial receptors. The team obtained multi-dimensional microscale or nanoscale self-assembly architectures: 0D micelles, 1D nanofibers, 2D nanosheets, and 3D nanorods and vesicles. They discovered that the host size has an impact toward self‐assembly morphology.

The team also discovered that the developed self-assembly systems undergo morphology conversions under UV irradiation. When irradiated by UV‐light, azobenzene‐moiety had an E‐to‐Z transition, which led to the morphology conversion of self‐assemblies. In addition, UV‐induced cargo release was investigated. This could make the self-assembly systems useful carriers for biological and medicinal applications.


Article Views: 1403

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

Bookmark and Share

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission. more


ChemistryViews.org on Facebook

ChemistryViews.org on Twitter ChemistryViews.org on YouTube ChemistryViews.org on LinkedIn Sign up for our free newsletter

Magazine of Chemistry Europe (16 European Chemical Societies)published by Wiley-VCH