In this issue, V. Gouverneur et al. review the fluorination of C–H bonds. How did this technique emerge as a powerful method for accessing functional molecules such as pharmaceuticals or PET radiotracers? The Minireview by H. Altug et al. deals with metasurface-based molecular biosensing aided by artificial intelligence. In an Essay, C. Wentrup writes on the history of preparation and uses of fulminating gold and silver from the late 1500s onward.

In the original research section, G. A. Ozin et al. describe the production of graphene quantum dots from the papermaking waste black liquor. J. R. Walensky et al. report the synthesis and utility of a neptunium(III) hydrocarbyl complex. S. E. Reismanet al. detail the nickel-catalyzed conversion of enol triflates into alkenyl halides. B. M. Trost et al. elaborate complex heteroaryl-containing cyclesvia enantioselective palladium-catalyzed cycloadditions.

• Angewandte Chemie 42/2019: Onward!,
  Angew. Chem. Int. Ed. 2019, 58 (42).