Chiral Nanosheets for Enantiomeric Separation

  • Author: Angewandte Chemie International Edition
  • Published Date: 10 July 2020
  • Source / Publisher: Angewandte Chemie International Edition/Wiley-VCH
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
thumbnail image: Chiral Nanosheets for Enantiomeric Separation

Most porous 2D nanomaterials are achiral, and thus, their pores do not respond to chiral molecules. Chiral nanosheets are challenging to construct. However, such materials are desirable because they can be used for fast and efficient enantiomer separation.


Using a self-assembly process, Myongsoo Lee, Jilin University, Changchun, and Fudan University, Shanghai, both China, and colleagues have created single-layered, 2D porous sheets with two types of chiral void spaces. A plate-like aromatic amphiphile containing hydrophilic flexible chains (1, pictured below) was used. This compound forms stable 2D nanosheets in an aqueous methanol environment. The aromatic segments of 1 are stacked in a slip-and-tilt manner (pictured below) to form clusters. The clusters from sheets with an alternating "up" and "down" arrangement of the clusters (pictured in blue and red). This results in a chiral superstructure with a chiral environment in the pores.


The chiral sheets made from (S)-1 or (R)-1 selectively take up the L- or D-enantiomers, respectively, of a racemic tartrate derivative within minutes. They absorb the target enantiomer with greater than 99 % ee. According to the team, this work could be a basis for the construction of superfast separation materials with excellent enantiomer selectivity.

 


 

 

Article Views: 901

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

Bookmark and Share

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission. more


CONNECT:

ChemistryViews.org on Facebook

ChemistryViews.org on Twitter ChemistryViews.org on YouTube ChemistryViews.org on LinkedIn Sign up for our free newsletter


Magazine of Chemistry Europe (16 European Chemical Societies)published by Wiley-VCH