Ei-ichi Negishi (1935 – 2021)

Ei-ichi Negishi (1935 – 2021)

Author: ChemistryViews

Professor Ei-ichi Negishi, Purdue University, West Lafayette, IN, USA, passed away on June 6, 2021.

Negishi was awarded the Nobel Prize in Chemistry 2010 together with Richard F. Heck and Akira Suzuki for “palladium-catalyzed cross couplings in organic synthesis”. He is best known for the Negishi coupling, a transition-metal-catalyzed reaction of organic halides or triflates with organozinc compounds. His main areas of work were palladium- or nickel-catalyzed coupling reactions as well as carbometallations of alkenes and alkynes.


Ei-ichi Negishi was born in Hsinking (today’s Changchun, China), Manchukuo, in 1935. In 1958, he graduated from the University of Tokyo, Japan, where he had majored in non-biological sciences and engineering, and became a research chemist at Teijin Limited, Japan. In 1960, he received a Fulbright Scholarship and went to the University of Pennsylvania, Philadelphia, USA, as a graduate student. Ei-ichi Negishi obtained his Ph.D. there in 1963 for work in synthetic organic chemistry under the supervision of Allan R. Day.

In 1966, he became a postdoctoral researcher at Purdue University, West Lafayette, IN, USA, where he worked with Herbert C. Brown. In 1972, he joined Syracuse University, NY, USA, as Assistant Professor. Ei-ichi Negishi was promoted to Associate Professor there in 1976. He returned to Purdue University as Full Professor in 1979. In 1999, he was named the Inaugural Herbert C. Brown Distinguished Professor of Chemistry.

Among many other honors, Ei-ichi Negishi has received the Chemical Society of Japan (CSJ) Award in 1996, the Humboldt Senior Researcher Award and the American Chemical Society (ACS) Organometallic Chemistry Award in 1998, the Royal Society of Chemistry (RSC) Sir Edward Frankland Prize Lectureship in 2000, the ACS Award for Creative Work in Synthetic Organic Chemistry and the Nobel Prize in Chemistry in 2010, as well as several honorary doctorates. Negishi was a Member of the American Academy of Arts & Sciences and a Foreign Associate of the U.S. National Academy of Sciences. He also was a member of the Honorary Board of the Asian Journal of Organic Chemistry.

Selected Publications


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