In this issue, R. V. A. Orru et al. discuss multicomponent reactions as a path to molecular complexity and diversity in a Review. Are such reactions discovered purely by serendipity or can they be designed rationally? In a Minireview, M. Bella et al. elaborate on multiple catalysis with two chiral units. The Highlights deal with hydrocarboxylation of alkenes and alkynes with CO2 (Y. G. Zhang und S. N. Riduan) and two-coordinate transition-metal centers with metal–metal bonds (P. L. Holland).
In the Communications section, J. Sun et al. present an actuator that walks steadily on a substrate and is driven by humidity changes (see picture). I. Honma et al. observed a transition between ferro- and paramagnetism in a Prussian blue analogue that depends on its lithium ion content. S. Doye et al. succeeded in elucidating the mechanism of the titanium-catalyzed hydroaminoalkylation of alkenes.