Advance Towards New Biobased Performance Materials

  • ChemPubSoc Europe Logo
  • Author: ChemViews
  • Published Date: 04 December 2011
  • Source / Publisher: ChemSusChem/Wiley-VCH
  • Copyright: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
thumbnail image: Advance Towards New Biobased Performance Materials

Related Societies

The family of 1,4:3,6-dianhydrohexitols, also known as isohexides, have proven to be excellent building blocks for the production of high performance biobased polymers such as polyamides and polyurethanes, owing to their intrinsic rigidity. The sugar based diols exist as three different stereoisomers: 1,4:3,6-dianhydro-d-glucidol (isosorbide), 1,4:3,6-dianhydro-dmannitol (isomannide), and 1,4:3,6-dianhydro-l-iditol (isoidide), derived from D-glucose, D-mannose, and L-fructose, respectively.

Daan S. van Es, Wageningen University & Research Centre, The Netherlands, developed a new, facile and scalable three-step route to obtain high purity dideoxy-diamino isohexides with absolute stereocontrol. The synthetic strategy encompasses three steps: transformation of the hydroxyl functionalities into efficient leaving groups, nucleophilic substitution with a protected amine, and catalytic removal of the protecting group, yielding the free amine.

The improved synthetic route is a valuable advance towards meeting scale and purity demands for evaluating the properties of new biobased performance materials, which will benefit the development of plastics.

Article Views: 3089

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

Bookmark and Share

If you would like to reuse any content, in print or online, from, please contact us first for permission. more

CONNECT: on Facebook on Twitter on YouTube on LinkedIn Sign up for our free newsletter

A product of ChemPubSoc Europe (16 European Chemical Societies)published by Wiley-VCH