In this issue, G. Van Tendeloo et al. review the 3D characterization of noble-metal nanoparticles and their assemblies by electron tomography. How does this technique help to understand the connection between the properties and structure or composition of nanomaterials? In another Review, A. C. Conibear and D. J. Craik discuss the chemistry and biology of theta defensins. What are their applications and how are they biosynthesized and distributed in primates? In a Minireview, R. J. Thomson et al. summarize the total synthesis of isodon diterpenes. The Highlights deal with supramolecular polymerization (Q. Zhang and H. Tian) and antibody conjugation (P. M. P. Gois et al.).
In the Communications section, F. X. Gomis-Rüth et al. demonstrate how multiple stable conformations account for reversible oligomerization and autoinhibition of a metamorphic metallopeptidase (see picture). M. V. Fedin et al. observed ultrafast photoswitching in a copper nitroxide based molecular magnet. H. S. Choi et al. present phosphonated near-infrared fluorophores for bone imaging, and V. K. Singh et al. report on an entry to enantiomerically enriched isoindolinones.
- Angewandte Chemie 40/2014: Rich Chemistry,
Angew. Chem. Int. Ed. 2014, 40.