A Complex Issue

A Complex Issue

Author: Angew. Chem. Int. Ed.

Amouri and co-workers have described the synthesis, isolation, and characterization of a new η4-diseleno-p-benzoquinone compound that is stabilized by coordination to an Cp*Ir moiety.

This organoselenium complex, [Cp*Ir(η4-C6H4Se2)], was prepared by using a template already coordinated to the Ir fragment, and thereby giving a molecule that has been elusive for several years. NMR spectroscopy and X-ray analysis data support stabilization of this reactive diselenobenzoquinone species by metal-to-ligand π backbonding.

They have also shown that this organoselenium compound has notable biological activity compared to the related quinone and thioquinone complexes, and is on a par with the cytotoxic activity of cisplatin—a promising starting point for further study.

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