• Author: ChemViews
  • Published Date: 22 July 2010
  • Source / Publisher: European Journal of Organic Chemistry/Wiley-VCH
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
thumbnail image: Two-For-One

Related Societies

Triethylphosphane hydrobromide in its reaction with dimethyl acetals leads to α-methoxy phosphonium salts as has been reported by Priyabrata Das and James McNulty, McMaster University, Ontario, Canada. However, under the same conditions, triphenylphosphane hydrobromide was shown to be methylated giving the corresponding quaternary methyl(triphenyl) phosphonium salt.

They also report that the ylide formation/olefination reactions from the α-methoxy phosphonium salts formed in this manner, could be employed in the synthesis of a wide range of vinyl ethers and variously functionalized 1,3-dienes.

The production of quaternary phosphonium salts using this general P-methylation process avoids the use of toxic alkylating agents. Further investigations into the preparation and reactivity of these salts and applications of the vinyl ether products are under investigation.

Article Views: 2949

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from, please contact us first for permission and consult our permission guidance prior to making your request

Follow on Facebook Follow on Twitter Follow on YouTube Follow on LinkedIn Follow on Instagram RSS Sign up for newsletters

Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH