Hydrogenases Get Se-rious

  • Author: David Smith
  • Published Date: 28 April 2015
  • Source / Publisher: Chemistry – A European Journal/Wiley-VCH
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
thumbnail image: Hydrogenases Get Se-rious

Related Societies

[NiFeSe] hydrogenase enzymes are particularly suitable catalysts for H2 evolution, because they exhibit high catalytic activities and fast reactivation from O2 inactivation compared with their thiolate analogues and other hydrogenases. This is thought to be caused by the selenium residue.

To investigate the reactivity of [NiFeSe] hydrogenases, Claire Wombwell and Erwin Reisner, University of Cambridge, UK, synthesized a dinuclear model of the [NiFeSe] hydrogenase active site, namely [NiFe('S2Se2')(CO)3] (H2'S2Se2'=1,2-bis(2-thiabutyl-3,3-dimethyl-4-selenol)benzene). The model compound (pictured) was generated by the reaction of a nickel selenolate complex with [Fe(CO)3bda] (bda = benzylideneacetone).

The team characterized the complex spectroscopically and electrochemically, and investigated its electrocatalytic activity for H2 evolution. According to the researchers, the catalytic effect does not result from homogeneous catalysis, but from a solid deposit containing Ni, Fe, S, and Se formed from the complex on the electrode surface when a potential was applied. The model compound thus acts as a precursor for a heterogeneous catalyst.


Article Views: 3545

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission and consult our permission guidance prior to making your request

Follow on Facebook Follow on Twitter Follow on YouTube Follow on LinkedIn Follow on Instagram RSS Sign up for newsletters

Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH