Celiac Biosensor

  • Author: David Bradley
  • Published: 09 April 2011
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
  • Source / Publisher: Analytical Chemistry/ACS Publications
thumbnail image: Celiac Biosensor

The autoimmune condition, celiac disease, causes sufferers to react with potentially debilitating effect to eating gluten, a protein found in wheat. A gluten-free diet in genetically susceptible individuals usually ensures a life free of symptoms. Now, researchers in Spain have developed a simple biosensor based on supramolecular chemistry that can detect the antibodies generated by people with celiac disease when they are exposed to gluten. The electrochemical is biosensor based on a cyclodextrin-modified gold surface can detect antigliadin antibodies in blood samples.

The biosensor could have diagnostic applications as well as allowing healthcare workers to ensure patients are complying with a gluten-free diet.

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