DNA Origami

  • Author: ChemistryViews
  • Published: 15 April 2011
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
  • Source / Publisher: Science/AAAS
thumbnail image: DNA Origami

DNA origami uses the self-assembling properties of DNA’s four complementary base pairs to form shapes such as stars, rhomboids, snowflakes, simple words and even maps. Hao Yan, Yan Liu and colleagues, Arizona State University, USA, have extended this to produce curved structures not possible before.

Simple 2-dimensional concentric rings were initially produced. These were bound together by strategically placed crossover points. Varying the number of nucleotides between crossover points and the placement of crossovers allowed control over the curvature. To demonstrate this, the team made spheres, hemispheres, ellipsoid shells, and a round-bottomed nanoflask.

The closed, 3D nanoforms could find use as delivery agents for the targeted and controlled release of drugs or as nanoreactors for chemical reactions — perhaps a task for the nanoflask?

Article Views: 3411

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission. more


ChemistryViews.org on Facebook

ChemistryViews.org on Twitter ChemistryViews.org on YouTube ChemistryViews.org on LinkedIn Sign up for our free newsletter

Magazine of Chemistry Europe (16 European Chemical Societies)published by Wiley-VCH