Adapt and Analyze

Adapt and Analyze

Author: David Bradley

Medical diagnostics and environmental monitoring will be revolutionized by cheap and portable monitors. Now, US researchers have adapted a glucose monitor to detect non-glucose analytes. The modification uses the enzyme invertase, which is released from a functional-DNA-invertase conjugate in the presence of the analyte. Invertase converts sucrose added to the sample to glucose, which is recorded as a proxy of the analyte concentration.

The researchers have successfully tested the modified device against a toxic metal, a disease marker and an illicit drug. It could be adapted easily for other compounds.

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