A Blood Test for Depression?

  • Author: Melania Tesio
  • Published: 11 October 2014
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
  • Source / Publisher: Translational Psychiatry/Macmillan Publishers Limited
thumbnail image: A Blood Test for Depression?

Depression is a psychiatric disorder widespread in western countries. Currently, the diagnosis of this disease is based on non-specific symptoms such as low mood, fatigue, lack of appetite, which also occur in numerous other mental or physical illnesses.

D. C. Mohr, Northeastern University, Chicago, USA, and colleagues developed a blood test to accurately diagnose depression in adults. By conducting a study on 32 depressed patients and 32 healthy control subjects, the researchers discovered that nine messenger RNA markers were present at high concentrations in the blood of depressed patients but at very low levels in healthy controls. The concentration of these messenger RNA markers also predicted the patients' response to therapies as they decreased in patients who were no longer depressed after 18 months of therapy.

Determining the blood concentration of these molecules may, therefore, provide an accurate diagnosis of depression and a means of monitoring the response to therapy.


Article Views: 2370

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

Bookmark and Share

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission. more


ChemistryViews.org on Facebook

ChemistryViews.org on Twitter ChemistryViews.org on YouTube ChemistryViews.org on LinkedIn Sign up for our free newsletter

A product of ChemPubSoc Europe (16 European Chemical Societies)published by Wiley-VCH