pH Sensing Goes Photoacoustic

  • Author: Xin Su
  • Published: 19 March 2015
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
  • Source / Publisher: Analytical Chemistry/ACS Publications
  • Associated Societies: American Chemical Society (ACS), USA
thumbnail image: pH Sensing Goes Photoacoustic

The photoacoustic effect refers to a phenomenon where light irradiation generates sound waves caused by heat release. It forms the basis for photoacoustic imaging, a highly desirable technique in biomedicine due to its non-invasive nature.

Guided by basic principles of photoacoustic imaging, Kevin W. Davies and colleagues at Florida Gulf Coast University, Fort Myers, FL, USA, have identified Nitrazine Yellow (NY) as an ideal reporter molecule for pH, a quintessential physiological parameter. As a pH-sensitive azo dye that is capable of rapid and quantitative light-to-heat conversion, NY shows well-behaved photoacoustic responses as a function of pH. In addition, NY’s performance is not interfered by turbid media, and its bioconjugates inherit such excellent photoacoustic properties, making them promising candidates for in vivo real-time pH imaging.


Article Views: 2654

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from, please contact us first for permission. more

Follow on Facebook Follow on Twitter Follow on YouTube Follow on LinkedIn Follow on Instagram RSS Sign up for newsletters

Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH