The ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogens cause an increasing number of nosocomial infections worldwide since they escape the inhibitory effect of the available antibiotics and the immune response.
Julian Davies and colleagues, University of British Columbia, Vancouver, BC, Canada, report the broad-spectrum and potent antibacterial activity of Kisameet clay against a group of multidrug-resistant ESKAPE strains. This is a natural clay mineral from British Columbia which has been used by the members of the Native Americans tribe First Nations. Tests showed that the clay in addition works efficiently against biofilms of MRSA and Pseudomonas aeruginsoa. Such accumulations of bacteria which are protected with mucus are particularly resistant to antimicrobials and are, therefore, difficult to control. The Kisameet Clay also has an antifungal effect.
The researchers think that this natural clay has potential to be developed as a therapeutic option for the treatment of infections due to multidrug-resistant organisms.
- Kisameet clay exhibits potent antibacterial activity against the ESKAPE pathogens,
S. Behroozian, S. L. Svensson, J. Davies,
mBio 2016, 7(1):e01842-15.