Structural diversity can be generated from α,β-unsaturated carbonyls via N-tosylhydrazones through a one-pot-three-component photochemically promoted carboborylation/allylic Suzuki sequence. The wide availability and scope regarding each of three reaction partners: carbonyls, alkylboronic acids, and aryl halides, and the functionalities available in the reaction products provide a powerful method for diversity-oriented synthesis.

[Research Article]
Álvaro Valdés-Maqueda, Manuel Plaza, Carlos Valdés
ChemistryEurope, https://doi.org/10.1002/ceur.202500212. Read article.

Ligand-to-metal charge transfer photocatalysis and benzenethiol-based hydrogen atom transfer catalysis are integrated to develop an iron-promoted anti-Markovnikov hydrochlorination of alkenes with hydrochloric acid. The results of experimental and theoretical analyses provide fundamental insights into reactivity control, paving the way for future reaction design.

[Research Article]
Subrata Mukherjee, Ayako Kubota, Shintaro Kawamura, Mikiko Sodeoka
ChemistryEurope, https://doi.org/10.1002/ceur.202500258. Read article.

Antioxidant, anti-inflammatory, cardioprotective, anti-apoptotic, immunomodulatory, neuroprotective, mitoprotective, antimicrobial and anticancer properties comprise the multitarget biological activity demonstrated so far investigating lemon, grapefruit, orange, red orange and mandarin IntegroPectin in both in vitro and in vivo studies. A critical perspective towards production and practical uptake of this new class of bioproducts for the treatment and prevention of numerous ailments concludes this account.

[Review]
Dr. Rosaria Ciriminna, Prof. Valentina Di Liberto, Dr. Lorenzo Albanese, Dr. Giovanna Li Petri, Dr. Chiara Valenza, Dr. Giuseppe Angellotti, Dr. Francesco Meneguzzo, Dr. Mario Pagliaro
ChemFoodChem, https://doi.org/10.1002/cfch.202500014. Read article.

BixMoy alloys are designed to electrocatalytic conversion of 15NO2- to 15N-oxime with a 76% Faradaic efficiency and 88% yield at 3.0 A. Mo serves as the H2O activation site, whereas Bi acts as the 15NO2- activation site. The synergy between Bi and Mo leads to a high 15N-oxime formation rate. Moreover, Mo introduction increases the hydrogenation energy barrier for 15NH2OH to 15NH3, suppressing 15NH2OH overhydrogenation and therefore improving 15N-oxime Faradaic efficiency.

[Research Article]
Jinghui Zhao, Dr. Rong Yang, Prof. Cuibo Liu, Prof. Bin Zhang, Prof. Yongmeng Wu
Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202516528. Read article.

Propylene-ethylene copolymer covalent adaptable networks (PEC CANs) are synthesized via one-step, radical-based reactive processing with the use of initiator, dynamic cross-linkers, and vinyl aromatic additives. The best CAN suppresses over 98% of creep at 100 °C (semicrystalline state) for 10,000 s compared to neat PEC. The same CAN is reprocessable either through compression molding or twin-screw extrusion.

[Research Article]
Yen-Wen Huang, Mathew J. Suazo, Stephanie M. Barbon, Hayley A. Brown, Evelyn Auyeung, Colin Li Pi Shan, John M. Torkelson
ChemSusChem, https://doi.org/10.1002/cssc.202501137. Read article.

This study presents novel, highly tunable chiral phosphoric acids (CPAs) with a decahydroquinoxaline scaffold, synthesized via stereoselective pinacol coupling of Salen-like bisimines from aromatic aldehydes and enantiopure trans-1,2-diaminocyclohexane. These CPAs catalyze the enantioselective Friedel-Crafts addition of indoles to N-tosylimines, achieving high yields and excellent enantioselectivity.

[Research Article]
Margherita Gazzotti, Manuel Orlandi, Sergio Rossi, Laura Raimondi, Maurizio Benaglia
ChemistryEurope, https://doi.org/10.1002/ceur.202500234. Read article.

A multi-component electrolyte composed of Zn(ClO4)2, ZnCl2, glycerol (Gly), and polyvinyl alcohol (PVA) enables highly reversible four-electron aqueous zinc-iodine batteries over a wide temperature range. Gly and PVA synergistically disrupt the intrinsic H-bond network and reduce the active water content. The PVA-containing dual-salt system effectively activates and stabilizes the I0/I+ redox reaction even under low chloride concentrations.

[Research Article]
Xiansheng Luo, Prof. Lifang Jiao, Prof. Dongliang Chao, Prof. Fujun Li, Dr. Rui Wang, Dr. Shilin Zhang, Quanwei Ma, Assoc. Prof. Hongbao Li, Dr. Longhai Zhang, Prof. Chaofeng Zhang
Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202514375. Read article.

The covalent integration of polythiophene chains into COFs enables the transformation of 2D structure into a well-defined, highly conductive 3D framework. This molecular weaving strategy not only significantly enhances electrical conductivity but also induces pronounced HOMO-LUMO spatial separation, increases active site density, and ultimately leads to superior photocatalytic performance in quinazolinone photosynthesis.

[Research Article]
Dr. Qian-Qian Huang, Dr. Ning Li, Man-Shi Han, Prof. Jiang Liu, Prof. Ya-Qian Lan
Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202513848. Read article.

A high-valent terminal iron-oxo species of a µ-nitrido-bridged iron phthalocyanine dimer is so reactive that it can oxidize the stable CH bond of methane in an aqueous solution. Fixation of a µ-nitrido-bridged iron phthalocyanine dimer on a highly oriented pyrolytic graphite surface, followed by treatment with aqueous H2O2, enabled us to observe the high-valent iron-oxo species directly at room temperature by various spectroscopies including matrix-assisted laser desorption and ionization-time-of-flight mass spectroscopy, X-ray photoelectron spectroscopy, soft X-ray absorption spectroscopy, and resonance Raman spectroscopy.

[Research Article]
Yasuyuki Yamada, Yuka Toyoda, Masanari Nagasaka, Naoki Nakatani, Takanori Koitaya, Akiyoshi Kuzume, Kentaro Tanaka
ChemistryEurope, https://doi.org/10.1002/ceur.202500277. Read article.

In this Highlight, recent reports are presented featuring three unique catalysts—Ir-based, TXT, and Al-Salen—demonstrating how the EnT process can generate triplet diradicals to form attractive cyclic architectures via intramolecular cyclization. Extensive experimental and theoretical studies have provided valuable insights, informing future strategies and potential implementations.

[Highlight]
Nirbhik Chatterjee
Asian Journal of Organic Chemistry, https://doi.org/10.1002/ajoc.70170. Read article.

The working mechanism of a specific pH-responsive luminescence probe, Ratio-pHCL-1, is studied using density functional theory and Marcus theory. The study reveals a three-stage mechanism involving pH-driven structural changes, gradually reversible charge-transfer initiated luminescence, and intramolecular energy transfer. The findings explain the origin of ratiometric chemiluminescence and offer insights for designing new types of pH-responsive luminescence probes.

[Research Article]
Shuangqi Pi, Ya-Jun Liu
ChemPhysChem, https://doi.org/10.1002/cphc.202500437. Read article.

Conventional Pt/Mn3O4 catalyst suffers from sluggish hydrogen spillover due to strong Pt─H binding at interfacial Ptδ+─O─Mn sites. In contrast, the Mn3O4/Pt inverse catalyst enables more efficient hydrogen spillover and enhanced CO2 hydrogenation, owing to weaker H adsorption and a more favorable transition-state geometry along interfacial Pt─Mn─O pathway.

[Research Article]
Xiaoyu Liang, Dr. Cui Dong, Dr. Le Lin, Yingjie Wang, Youyuanhe Yang, Dr. Rankun Zhang, Dr. Dongqing Wang, Xi Cheng, Prof. Rentao Mu, Prof. Qiang Fu
Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202515905. Read article.

Nitric oxide induces decomposition of electron-deficient aminoferrocene drugs 4 with formation of oxime 7, which is derived from the upper cyclopentadienyl ligand. Drugs 4 are not responsive to hydrogen peroxide. Based on the latter reaction, the fluorogenic probes are developed for detecting NO in cells and inflammation in vivo.

[Research Article]
Roman Selin, Hülya Gizem Özkan, Galyna Bila, Rostyslav Bilyy, Andriy Mokhir
ChemMedChem, https://doi.org/10.1002/cmdc.202500356. Read article.

This manuscript presents a series of eight small compounds based on the α-cyanostilbene motif and with different substituents. Three of these compounds show good rates of chloride transport, as well as selectivity for chloride over hydroxide, bicarbonate, and fluoride anions.

[Research Article]
Dr. Anurag Singh, Dr. Lau Halgreen, Priyanka Rani Panda, Dr. Aaron Torres-Huerta, Dr. Nikolay Tumanov, Prof. Johan Wouters, Dr. Hennie Valkenier
Chemistry ? A European Journal, https://doi.org/10.1002/chem.202502050. Read article.

Operando substrate curvature measurements are used to monitor the mechanical stress of hard carbon composite electrodes during sodiation and desodiation. The observed asymmetry of the electrode volume between sodiation and desodiation is explained by an interaction between sodium intercalation and pore filling: during pore filling, the sodium concentration in the transport paths is higher than during pore depletion.

[Research Article]
Stefan Mück, Dominik Kramer, Krishnaveni Palanisamy, Christine Kranz, Reiner Mönig
ChemSusChem, https://doi.org/10.1002/cssc.202501272. Read article.

The influence of the length of the aromatic walls of methylene-bridged glycoluril-dimer-derived molecular clips on their binding affinity toward a panel of planar aromatic cations is reported. We find that anthracene-walled host H2 generally binds ≈ 10-fold stronger to a specific guest than naphthalene-walled H1.

[Research Article]
Collin J. Vincent, Dr. David King, Dr. Steven L. Murkli, Prof. Dr. Lyle Isaacs
Chemistry ? A European Journal, https://doi.org/10.1002/chem.202502177. Read article.

Idealized models such as the Wulff construction provide inaccurate structures for small supported nanoparticles (NPs). Global optimization via machine learning interatomic potentials (MLIPs) enables finding reshaped, more realistic, and more stable structures in quantitative agreement with microcalorimetric measurements.

[Research Article]
Tristan Maxson, Prof. Dr. Tibor Szilvási
Angewandte Chemie Novit 2025, 1, 0. Read article.

A plasmonic Au@Au3Pd catalyst that integrates visible-light-driven hot electron generation with bimetallic electronic tuning to steer the selective hydrogenation of cinnamaldehyde toward propylbenzene is reported. Localized surface plasmon resonance excitation modulates reaction pathways on tailored Au-Pd interfaces, enabling product selectivity under mild conditions.

[Research Article]
Sana Frindy, Shiqi Wang, Sam Sullivan-Allsop, Rongsheng Cai, Thomas J. A. Slater, Sarah J. Haigh, Pedro H. C. Camargo
ChemSusChem, https://doi.org/10.1002/cssc.202501054. Read article.

Non-noble metal complexes are employed as co-catalysts of m-TiO2 to improve the photocatalytic production of green hydrogen from water photolysis. Six new copper(I) pyridinium-selenolate complexes have been fully characterized and utilized for the development of photocatalysts intended for heterogeneous photocatalysis.

[Research Article]
Leonardo Carneiro Lanes, Rodrigo Cervo, Robert Alan Burrow, Bernardo Almeida Iglesias, Natália de Freitas Daudt, Ernesto Schulz Lang, Bárbara Tirloni, Roberta Cargnelutti
European Journal of Inorganic Chemistry, https://doi.org/10.1002/ejic.202500295. Read article.

HgCl2(C3N6H6), a layered hybrid material, is obtained by combining mercury(II) chloride and melamine in a hydrothermal synthesis. It crystallizes in a non-centrosymmetric structure and exhibits strong second-harmonic generation. The thermally stable compound features a distorted octahedral coordination environment of mercury ions. Structural, spectroscopic, and density functional theory analyses highlight its potential as a nonlinear optical material.

[Research Article]
Melena Groß, Patrick Schmidt, Carl P. Romao, David Enseling, Thomas Jüstel, Mykhailo Brytskyi, Scott Kroeker, Hans-Jürgen Meyer
European Journal of Inorganic Chemistry 2025, 0. Read article.