Herein, direct deoxygenative borylation of acyl chlorides is reported, which is an unknown but desirable chemical transformation. The N-heterocyclic nitrenium ion has been utilized as the photocatalyst under mild reaction conditions to synthesize a series of alkylboronates using bis-(catecholato)diboron (B2cat2) as the diboron reagent. The reaction follows a radical pathway, with breaking of the CO bond as the key step.

[Research Article]
Rahul Mondal, Apurba Kumar Pal, K. Geetharani
ChemistryEurope, https://doi.org/10.1002/ceur.202500093. Read article.

CH H bonds (HB) are normally much weaker than those involving the OH group. Quantum chemical calculations address the sorts of substituents, and their placement, that might adjust the strengths of the OH··N and CH··N HBs to make them more nearly equal.

[Research Article]
Savannah Rawlings, Steve Scheiner
ChemistryEurope, https://doi.org/10.1002/ceur.202500088. Read article.

Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron-deficient cores. Nevertheless, they are now extending their application to biology. In this review, the synthesis of BXDs and their use in medicinal chemistry as lipophilic aromatics and in photomedicinal chemistry as photosensitizers will be presented.

[Review]
Jean-Elie Zheng, Xavier Franck, Thibault Gallavardin
European Journal of Organic Chemistry, https://doi.org/10.1002/ejoc.202500228. Read article.

An indole synthesis via an allenyl ester intermediate at ambient temperature has been developed. The mild reaction conditions allow the use of a broad range of substrates. Notably, the utility of this approach is demonstrated through the asymmetric total synthesis of geissoschizoline, a Strychnos-type monoterpenoid indole alkaloid. This synthesis highlights a novel strategy for accessing monoterpenoid indole alkaloids.

[Research Article]
Sohsuke Moriue, Honami Nishioka, Yuto Fukuda, Hiromitsu Takayama, Mariko Kitajima, Hayato Ishikawa
ChemistryEurope, https://doi.org/10.1002/ceur.202500129. Read article.

We present high-frequency/high-field EPR spectroscopy studies on a series of pentagonal-bipyramidally coordinated ErIII(DAPMBH/H2DAPS)X complexes with different apical ligands (X = (H2O)Cl (1), (CH3OH)N3 (2), Cl2 (3)) to directly determine the electronic properties of the ground state and low-energy Kramers doublets, namely effective g-tensors and zero field splittings. Our findings are compared to the results of numerical studies and are used to rationalise the observed differences in magnetic relaxation behavior.

[Research Article]
Jan Arneth, Dr. Lena Spillecke, Dr. Changyun Koo, Dr. Tamara A. Bazhenova, Prof. Dr. Eduard B. Yagubskii, Prof. Dr. Rüdiger Klingeler
Chemistry ? A European Journal, https://doi.org/10.1002/chem.202500369. Read article.

Highly selective light-driven CO2 conversion to CO is achieved using an [FeFe]-hydrogenase-inspired molecular dyad (PS-CAT) acting simultaneously as photosensitizer and catalyst. The presence of water as a solvent is important for such selectivity. Assembling the PS-CAT in the hydrophobic part of lipid bilayers of liposomes allows the use of water as a solvent, static excited state quenching and high turnover numbers.

[Research Article]
Amir Abbas, Chizuru Kasahara, Yongchao Chen, Martin Oschatz, Stefanie Gräfe, Wolfgang Weigand, Andrea Pannwitz
ChemCatChem, https://doi.org/10.1002/cctc.202401947. Read article.

A daisy chain compound lacking intercomponent recognition motifs is synthesized and analyzed. As a result of the absence of intercomponent recognition motifs there was also no preferred conformation of the interlocked components observed.

[Research Article]
Dr. Charlotte Kress, Prof. & Dr. Daniel Häussinger, Prof. David A. Leigh, Prof. & Dr. Marcel Mayor
Chemistry ? A European Journal, https://doi.org/10.1002/chem.202501369. Read article.

An effective strategy is developed to stabilize lattice oxygen in 2D amorphous RuOx through p-p orbital hybridization by incorporating dopants such as Al, Ga, and In, which facilitates the switch from the lattice oxygen mechanism to the adsorbate evolution mechanism. In contrast, doping with other elements, such as Mn, Co, or Cu, results in negligible improvements in catalytic performance.

[Communication]
Dr. Yajing Mu, Prof. Dantong Zhang, Dr. Tianyi Gao, Dr. Lina Wang, Prof. Lei Zhang, Prof. Xiaoxin Zou, Prof. Weitao Zheng, Prof. Jinchang Fan, Prof. Xiaoqiang Cui
Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202505908. Read article.

Designing artificial enzymes remains challenging due to the need for precise active site control. Here, we present a simple strategy to create metal-free artificial enzymes by engineering Histidine clusters inside a ferritin cage. The resulting catalyst mimics peroxidase activity, and its stable cage structure offers new insights into supramolecular catalysis, opening avenues for bioinspired catalyst development.

[Research Article]
Jiaxin Tian, Basudev Maity, Tadaomi Furuta, Tiezheng Pan, Takafumi Ueno
Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202504608. Read article.

We presented a “polycondensation−depolymerization−repolymerization” strategy for structurally diverse aliphatic polycarbonates. This involved a step growth polycondensation of dialkyl carbonate and diol to low-molecular-weight polymers which are utilized to produce cyclic carbonates through catalytic depolymerization. The subsequent ring-opening polymerization of cyclic carbonate led to high molecular weight (>100 kDa) polycarbonates.

[Research Article]
Wei-Ning Liu, Mingqian Wang, Zhiqiang Ding, Yuesheng Li, Bin Wang
Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202505333. Read article.