Vitamin B12-catalyzed transformation of a wide range of substrates, from small molecules to proteins

Electrochemical Reduction of Disulfides

Can Large Language Models Predict Inorganic Syntheses?
Fine-tuned large language models (LLMs) found to perform similar to or better than specialized machine learning models for certain chemical tasks

Hydride-Free Copper Nanocluster for Catalysis
Atomically precise, luminescent copper nanocluster can promote photoinduced C–C coupling reactions

How Do Capping Agents Affect the Redox Potential of Nanoparticles?
Substantial potential differences observed between identical gold nanoparticles with 2- or 4-mercaptobenzoic acid ligands

Enantioselective Hydroxylation of Tertiary Propargylic C–H bonds
Manganese-catalyzed enantio-differentiating hydroxylation in acyclic systems

Vanadium-Dependent Chloroperoxidase for Regioselective Halogenation
Lavanducyanin halogenase (LvcH) discovered and used in chemoenzymatic synthesis

Copper-Catalyzed Amination of Base-Sensitive Aryl Bromides
Expanding the scope of copper-catalyzed C–N coupling reactions

A New Path to Benzocycloheptenes
Base-promoted (5+2) annulation of 2-(alkynylaryl)acetonitriles and arylalkynes

Nickel Catalysis for Asymmetric Aryl Addition to Sulfinylamines
Nickel catalyst with a chiral bisoxazoline ligand for the 2,3-addition of arylboronic acids to sulfinylamines

Triarylimidazole-Based Drugs Activated by Light
New strategy for caging bioactive triarylimidazoles uses a dialkylamino unit as a photoremovable group