New method for adding methyl groups to aldehydes gives the highest enantioselectivities and yields reported and can be used for longer alkyl chains

Production of 5-hydroxymethylfurfural (HMF) from fructose with a yield of up to 87 %

Designing small-molecule ligands for class B GPCRs despite the lack of structural information for this receptor class

Simple way to recover and reuse chiral copper bis(oxazoline) complexes reported by French researchers

Screening existing library of antagonists for binding affinity toward CD22 identifies new potential treatments for B-cell lymphomas

Canadian researchers have found a way to eliminate the liabilities of COX-2-specific inhibitors by introducing NO donor groups

Prediction of the melting point of ionic liquids could allow structural refinement before the first synthesis

Comprehensive comparison of hollow-fiber membranes for 129Xe NMR spectroscopy could improve setup

Software screens virtual multi-component reaction products which can be rapidly synthesized and undergo a reality check by physical screening

Lipid chain length could explain why some pathogens trigger an immune response while others evade immune recognition