The modification of ferrociphenol by appending a phosphine moiety to the cyclopentadienyl ring (initially unsubstituted) of the ferrocene unit offers a new and promising approach to enhancing this anticancer agent and enables the synthesis of novel biologically active derivatives.

What insights can we get from a daisy chain structure without a preferential low-energy arrangement of mechanically linked components?

A nickel-catalyzed method for the hydro- and deuterodehalogenation of (hetero)aryl halides under aqueous micellar conditions achieves high efficiency and excellent yields in over 40 examples.

Highlights from Chemistry Europe, ACES, and GDCh journals

Lutz Ackermann and colleagues have introduced a new class of chiral oxazoline ureas as κ²-N,O-preligands for enantioselective transition metal catalysis

Chemoselective thioamidation of potassium acyltrifluoroborates (KATs) and amines using elemental sulfur in aqueous solution

F. Inagaki and R. Murakami discuss a recent study demonstrating that CO₂ can be spontaneously released from aralkylamine–CO₂ complexes, representing a promising advancement in CO₂ capture technology

A fully enantioselective total synthesis of ectocarpin A, a new oxylipin, in 12 steps starting from tetrahydro-1H-cyclopentafuranone

Azadiene-linked COFs with extended π-conjugation act as efficient, metal-free photocatalysts for selective oxidations

Luísa Martins, Portugal, discusses a recently published study exploring the effects of catalysts, solvents, and reducing agents on the reaction kinetics of nitroarene reduction