Highlights from Chemistry Europe, ACES, and GDCh journals

Most Accessed Articles: October 2024

Binding RNA Drug Targets Using Spirocycles
New azaspirocycles with potential applications in drug discovery

Triel Bonds: New Pathway to Pentacoordinate Carbon
Study provides the first evidence of a pentacoordinate carbon in a stable complex, offering insights relevant to chemical bonding and biological methyl transfer processes

Selective Photocatalytic Benzene Oxidation
Iron-carbon nitride fragments used for the conversion of benzene to phenol

Synthesis of Axially Chiral Diaryl Aldehydes
Chiral phosphoric acid catalyst promotes formation of useful precursors for the synthesis of axially chiral compounds

“Bushy-Tailed” Disinfectants
Multicationic quaternary phosphonium compounds act as novel disinfectants with potent bioactivities and low toxicity

New Tetracyclic Ring Systems Synthesized
Five new heterocyclic ring systems that could have uses in medicinal chemistry

A New Chapter in Magnetism: The Role of Symmetry in Luminescent Yb3+ Complexes
Although the prolate single molecule magnets known from the textbook have large ground state splittings, this does not lead to strong magnetism

Silylation and Germylation of Azauracils
New protocol can be used for the late-stage functionalization of complex, drug-like molecules under mild conditions

New Cleavable Linker Design for Targeted Drug Therapy
Physiological thiol gradient between extra- and intracellular areas used to trigger novel cleavable linkers