
Light-Activated ONOO⁻ Generator for Targeted Biofilm Therapy
Researchers developed a light-activated molecule that releases nitric oxide and peroxynitrite to efficiently treat biofilm infections

Affinity-Driven DNA Hydrolysis by Engineering Ln-MOF Nuclease Nanozymes
Lanthanide MOF nanozymes break the Lewis acidity dogma—the conventional belief that catalytic activity is primarily determined by metal ion Lewis acidity—revealing an affinity-driven strategy for highly efficient artificial nucleases

Thiolate-Templated Construction of Aromatic Silver Nanoclusters
Construction of highly stable Ag₃₄ nanoclusters via a dual-exchange strategy, exhibiting high-efficiency near-infrared electroluminescence in NIR-OLEDs

Interfacial Supramolecular Polymerization Enables 2D Hierarchical Architectures
A novel interfacial polymerization strategy allows precise formation of two-dimensional hierarchical architectures with enhanced exciton migration and sensing performance

Breaking the NIR-IIx Barrier: Organic Small-Molecule Fluorophores for Deep-Tissue Imaging
Researchers develop bright, stable organic dyes that enable precise deep-tissue imaging and disease detection in the NIR-IIx spectrum

Supramolecular Nanocomplex Overcomes Drug-Resistant Liver Cancer by Inducing Dual-Site Ferroptosis
A natural nanocomplex overcomes drug resistance in liver cancer by inducing ferroptosis through a three-part mechanism that reduces glutathione in cancer cells, weakening their antioxidant defenses and causing cell death

Triplet Energy Transfer Nanocomposites for Highly Sensitive Prostate-Specific Antigen Detection
A luminescent nanoparticle assay enables ultra-sensitive detection of prostate-specific antigen for early diagnosis and recurrence monitoring
![Diazine-Tetraphenylethylene Cyclo[6]arenes for Molecular Recognition in Solution and Aggregate States](https://www.chemistryviews.org/wp-content/uploads/2025/11/ChemistryViews-2.70171-125x94.png)
Diazine-Tetraphenylethylene Cyclo[6]arenes for Molecular Recognition in Solution and Aggregate States
1,2-diazine endo-functionalized tetraphenylethylene cyclo[6]arenes for cation binding in dilute solution and nitrophenol detection in the aggregate state

Highly Photoluminescent RGB Carbon Dots for Lighting–Energy Applications
By precise molar ratio control strategy, tricolor carbon dots with high quantum yields are prepared for integrated lighting–energy applications

Aqueous Circularly Polarized Luminescence Regulated by α-Helix in Homopolypeptid
Chain length and self-assembly temperature of α-helix controls aqueous circularly polarized luminescence in homopolypeptide self-assembly

Resonance Energy Transfer Enables Chiral Recognition in the Solid State
Förster resonance energy transfer enables efficient, noncovalent chiral recognition in solid-state systems when host and guest share the same chirality

Covalent Bond Regulation in Nanographene: Precise Aggregation State Modification
Covalent bond regulation controls azulene-mediated nanographene aggregation via acids, while quenchers and temperature dictate product selectivity

Reversible Self-Assembly of Organic Nanoparticles with Fluorescence Modulation
Organic nanoparticles reversibly self-assemble and show fatigue-resistant fluorescence modulation, offering new opportunities for smart optoelectronics

AIEgen-Based Cystatin C Quantitation for Chronic Kidney Disease Monitoring
Cost-effective smartphone phosphorescence detection of cystatin C supports early warning and proactive care in chronic kidney disease

A New Tb Cluster Scintillator for Temperature-Independent X-ray Imaging
A terbium cluster scintillator, a material that converts X-rays into visible light, enables temperature-independent X-ray imaging with 23.3 LP mm⁻¹ resolutio
![Cucurbit[7]uril-Based Polymers with Dual Photochromism and Fluorescence](https://www.chemistryviews.org/wp-content/uploads/2025/09/70145-125x94.png)
Cucurbit[7]uril-Based Polymers with Dual Photochromism and Fluorescence
Cucurbit[7]uril-based complexes with tunable assembly show adjustable photochromism and fluorescence for multilevel anti-counterfeiting and encryption

Fast, Accurate, and Data-Efficient: The Future of Electron Density Prediction
GED-CRN model reaches MP2-level accuracy with only 19 training molecules, revolutionizing the design of aggregation-induced emission (AIE) materials with 1000x faster computation

Nile Red Derivatives-Mediated Phototherapy Against Pathogenic Microorganisms
TPAOMCN, a novel Nile Red derivative, demonstrates potent broad-spectrum phototherapeutic efficacy against multidrug-resistant bacteria and monkeypox virus

An NIR Fluorescent Probe for Assessing Lysosomal Function
Combining a lysosome-targeted near-infrared (NIR) probe with AI-driven image interpretation offers a scalable platform for high-resolution monitoring of lysosomal function