Small molecules targeting the nucleotide pool sanitization enzyme (MTH1) suppress tumor growth by inducing DNA damage

Useful Damage

The Biochemistry of Peppers
How is it that only plants from the genus Capsicum are able to synthesize compounds that sting one’s tongue so intensely?

Make Chemistry More Attractive
Dr. Thomas Geelhaar, the new President of the GDCh, will focus on working towards better acceptance of chemistry in society

Behind the Science: Small-Molecule Proteomimetic Inhibitors
Dr. M. Campbell, Associate Editor for ChemBioChem, talks to Professor A. Wilson, University of Leeds, UK, about his recent article

Chemical Poem: Bromine
Poems based on the natural properties of each of the elements of the periodic table

Amphotericin Derivatives on the Way?
A new mechanism of action of amphotericin B has been found and it may promote the development of less toxic derivatives

Angewandte Chemie 19/2014: Good Vibrations
Overview of the latest issue of Angewandte Chemie

Revealing the Essentials for Effective β-Glucopyranoside Recognition
A step forward in the design of synthetic receptors for the recognition of carbohydrates

C. Corminboeuf and J. Waser Awarded
The 2014 Werner Prize is shared between Clémence Corminboeuf and Jérôme Waser

Giant Vesicles from Sophorolipids
Sophorolipids based on linolenic acid self-assemble into giant-vesicle-type structures with membranes similar to those of cell walls