T. Hoffmann and R. Metternich, F. Hoffmann−La Roche Ltd., look at potential areas for drug R&D outside traditional medicinal chemistry

The Future of Medicinal Chemistry

Alcohol-Butadiene Hydrohydroxyalkylation
Direct redox-triggered carbon-carbon coupling sets stage for development of catalysts that exhibit enhanced stereoselectivities

Angewandte Chemie 19/2012: The Secret of Print
An overview of the latest issue of Angewandte Chemie

Silicon Nanosponges for Cellular Patterning
Microscopic patterning of mammalian cells using inorganic nanosponges could facilitate new tissue engineering technology

Stable Branched DNA G-Quadruplexes
The trebler phosohoramidite enables the synthesis of DNA quadruplexes with modifications on only one of the four strands

Unnatural Amino Acids
Engineering methylaspartate ammonia lyase has helped researchers with the asymmetric synthesis of unnatural amino acids

Guess the Chemist (5)
Can you guess the famous scientist from the description?

New Copper Coordination Compounds
Two Cu(II)-coordination compounds with tridentate aliphatic hydrazone ligand were characterized, and their biological effects tested

Michael Schütze on the Future of DECHEMA's Research
M. Schütze, Director DECHEMA Research Institute, talks about what the DECHEMA's reorganization means for the Research Institute

Combatting Designer Drugs Head On
New methods to help law enforcement keep up with the dizzying array of new designer drugs designed to escape detection