Chemoselective defluorinative [3+3] annulation gives dihydropyrimidine derivatives

Annulation of (Trifluoromethyl)alkenes and Thioureas

Solvent-Directed Regioselective Cascade Reaction of Diazo Compounds
Green, efficient, and regioselective synthesis of pyrazoles

Heavier Analogs of 1,2-Dihydrotetrazole
Experimental and theoretical investigation of the first diazadistiboylidenes

Most Accessed Articles: December 2024
Highlights from Chemistry Europe, ACES, and GDCh journals

Cascade Synthesis of Indole-Fused Benzodiazepines
Photocatalyzed reaction of α-acetoxy aryl ketones with o-indoloanilines

Neutral Boron Atom Stabilized by Only Neutral Ligands
Monoatomic boron(0) complex isolated at room temperature

Manganese-Catalyzed ortho-Deuteration of Aromatic Amidines
Efficient deuterium incorporation using D2O

Engineering a Decarboxylative Aldolase for the Synthesis of Cyclic Imino Acids
Divergent regioselectivity and diastereoselectivity compared to the wild-type enzyme achieved

Making Rhodamine B Dyes Using a Continuous Flow Method
Simple catalyst- and solvent-free protocol uses a single-screw mechanochemical approach

Multicomponent Synthesis Combines Spirooxindoles and Dihydropyridines
Catalyst- and solvent-free, microwave-assisted reaction of isatins, β-ketophosphonates, and primary amines