Overview of the latest issue of Angewandte Chemie

Angewandte Chemie 2/2025: Better Together

Supramolecular Snub Cubes
The cubes have external diameters of 5.1 nm, contain 2,712 atoms, and chiral cavities with volumes of 6,215 Å

Total Synthesis of Kasugamycin
Aminoglycoside antibiotic prepared from naturally derived carbohydrates

Late-Stage Diazoester Installation
Arylthianthrenium salts used for the introduction of diazo groups to densely functionalized arenes

Site-Selective Hydrogenation of Amides
Copper(I) N-heterocyclic carbene catalyst with an organocatalytic guanidine moiety for amide reduction

Angewandte Chemie 1/2025: New Year, Many Faces
Overview of the latest issue of Angewandte Chemie

Catalyst-Free N-Acylation of Azoles
Photochemical transformation using aldehydes with inexpensive BrCCl3 as the oxidant

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A Stable Acridinium-Based Radical
Synthesis of a stable radical via intramolecular photocyclodehydrogenation

Tuning Quantum Mechanical Tunneling Reactivity with Electron-Donating Substituents
Cláudio M. Nunes and Peter R. Schreiner discuss controlling quantum mechanical tunneling (QMT) reactivity by modifying electronic substituents and why QMT should be included in general chemistry curricula