Path to a natural product with a complex, fused hexacyclic scaffold

Total Synthesis of (+)-Mannolide B

8️⃣Which Nobel Laureate Lived in this House in Imperia, Italy?
Check out the answer to today's entry in the Chemistry Advent Calendar: Guess the Houses and Molecules—discover where famous chemists lived 🏠

Organocatalytic Path to Axially Chiral Spiro-Bisindoles
Intramolecular dehydrative cyclization catalyzed by a chiral phosphoric acid

Angewandte Chemie 51/2024: Stunning Views
Overview of the latest issue of Angewandte Chemie

An Electronically Controllable Sliding Molecular Machine
Movement of an ammonium-linked ferrocene on a copper surface can be controlled by an applied voltage

Modulating the Reactivity of Force-Sensitive Molecules
New strategy uses a ring-like structure to "pull" on a mechanophore with a tailored force

6️⃣Who Was the First to Synthesize This Molecule?
Check out the answer to today's entry in the Chemistry Advent Calendar: Guess the Houses and Molecules—discover who synthesized iconic molecules 🧪

Reusable MOF Catalyst for the Dehydrogenation of N-Heterocycles
Zinc-based metal–organic framework (MOF) with immobilized nickel centers used as recyclable heterogeneous catalyst

🎅🧪6️⃣Who Was the First to Synthesize This Molecule?
Chemistry Advent Calendar: Guess the Houses and Molecules—Discover who synthesized iconic molecules 🧪

Enantioselective Synthesis of Tri-Axis Naphthalenes
Sequential Diels–Alder reaction and dehydrative aromatization give axially chiral dyes