A concise synthesis of steviamine and three of its analogues is reported before testing for glycosidase inhibition

Sweet Route to Steviamine

Straightforward Hydrovinylation Approach to Dienes and Trienes
1,3-Dienes and 1,3,5-trienes can be formed simply by a microwave-accelerated Ru-catalyzed hydrovinylation of alkynes and enynes

2013 Wolf Prize in Chemistry
The 2013 Wolf Prize is awarded to Robert Langer, USA, for his work on controlled-release drug delivery systems

Anti-adhesive β-Cyclodextrin Complexes Reduce E. coli Infection
Heptavalent n-heptyl α-D-mannosides on β-cyclodextrin cores are shown to inhibit bacterial adhesion in vivo

Separation of Isomers by Milling
Separation of dicarboxylic acids through solid-state molecular recognition and mechanochemistry

Picture Competition – A Year in the Lab: The Chemist’s View
Submit your outstanding photo and have the chance to be selected for a calendar and win one of 12 exciting prizes

Preventing Geldanamycin’s Toxicity
Novel 19-substituted benzoquinone ansamycins inhibit heat shock protein 90 without causing toxic effects in vitro

Lactimidomycin – No Effect on Cell Motility but Still Cytotoxic
Synthesis and biological re-evaluation of the cytotoxic effects of Lactimidomycin and its progeny in cancer cells

Assisting C−H Activation
Detailed study into the mechanism for carboxylate-assisted C−H bond activation at Pd(IV) centers has been undertaken

Green Oxidations on Graphene
Graphene as an aerobic oxidation carbocatalyst derived from natural resources