Five new heterocyclic ring systems that could have uses in medicinal chemistry

New Tetracyclic Ring Systems Synthesized

Silylation and Germylation of Azauracils
New protocol can be used for the late-stage functionalization of complex, drug-like molecules under mild conditions

New Cleavable Linker Design for Targeted Drug Therapy
Physiological thiol gradient between extra- and intracellular areas used to trigger novel cleavable linkers

Death in a Pot: From England’s Famous Chemist to Exiled and Forgotten – Part 3
About the tragic fall of Fredrick Accum, the continuing importance of his work, and how things stand with food adulteration today

Nanozyme Microrobots for Treating Biofilm Infections
Microrobots driven by magnetic fields target and destroy hard-to-reach biofilms

Phototherapeutic Agent for the Noninvasive Threatment of Glioblastoma
Nanoparticles composed of an aza-BODIPY derivative and folic acid-grafted polymers serve as imaging probes and therapy agents

Sanofi to Prioritize Biopharma and Vaccine Development
CD&R to acquire a 50% stake in Opella, Sanofi’s consumer healthcare unit

Cell-Penetrating Peptides Deliver Antimalaria Drugs
Peptide-drug conjugates provide an approach for developing new malaria treatments

Bioprinter Could Soon Generate Body Parts in Space
An ESA-backed project aims to study cell growth in microgravity, advancing 3D bioprinting for space missions and biomedical research

New Cationic Antimicrobial Octapeptides
Tryptophan-containing members of an alternative class of antibiotics show broad-spectrum activities