Corinne Lionne and Elise Kaplan from Montpellier, France, discuss a new family of inhibitors they have discovered that reverse aminoglycoside resistance in Enterococcus strain

Overcoming Resistance to Aminoglycoside Antibiotics in Enterococcus

Total Synthesis of Ukabamide, a Drug Candidate against Sleeping Sickness
Lipopeptide from marine cyanobacteria could lead to new antitrypanosomal drugs

Nanobubbles for the Imaging and Treatment of Heart Disease
System for the noninvasive imaging and treatment of coronary microvascular dysfunction

Can 18F-PET Imaging Diagnose Multiple Sclerosis?
Design and synthesis of a sialic acid-derived tracer for 18F-PET MS imaging

Combining Prodrug Design With Nanotechnology for Improved Chemotherapy
New prodrug of gemcitabine synthesized and encapsulated in nanoparticles, significantly improving its anticancer efficacy in pancreatic and lung cancer cell lines

Polyglycerol Nanogels for Periodontitis Treatment
Dual-function nanogel combines antimicrobial and pro-angiogenesis medications to combat microbes and promote tissue regeneration

Most Accessed Articles: December 2024
Highlights from Chemistry Europe, ACES, and GDCh journals

A More Effective Way to Restore Blood Flow After Surgery
Why and how the polycationic γ-cyclodextrin PyA-γ-CD works better as anti-heparin coagulant than Protamine, the most commonly used drug

Angewandte Chemie 2/2025: Better Together
Overview of the latest issue of Angewandte Chemie

Supramolecular Snub Cubes
The cubes have external diameters of 5.1 nm, contain 2,712 atoms, and chiral cavities with volumes of 6,215 Å